Cai Dafeng, Vice Chairman of the Standing Committee of the National People’s Congress led a team to Anhui to carry out law enforcement inspection of science and technology progress law. Han Jun met wi

  (Reporter Zong He, reporter Li Mingjie Ban Hui) From July 3 to 7, Cai Dafeng, Vice Chairman of the Standing Committee of the National People’s Congress led a law enforcement inspection team to Anhui to carry out law enforcement inspection of the Law on Scientific and Technological Progress. Han Jun, Secretary of Anhui Provincial Party Committee, and Wang Qingxian, Governor of Anhui Province, met with the inspection team of law enforcement in Hefei.

  During the period of Anhui, the law enforcement inspection team held a forum to listen to the provincial government’s report on the implementation of the law and the acceleration of scientific and technological innovation, as well as the opinions and suggestions of some NPC deputies, experts and scholars. He went to Hefei, Ma ‘anshan, Wuhu and other places to conduct on-the-spot inspections in universities, research institutes, key laboratories and enterprises to learn more about the implementation of the Science and Technology Progress Law.

  Cai Dafeng fully affirmed Anhui’s achievements in conscientiously implementing the Law on Scientific and Technological Progress, firmly playing the "first move" in innovation, vigorously implementing the "tree planting project" in scientific and technological innovation, and accelerating the establishment of an application system for scientific and technological innovation and achievement transformation. He stressed that it is necessary to thoroughly study and implement the important exposition of the Supreme Leader General Secretary on scientific and technological innovation, conscientiously implement the decision-making arrangements of the CPC Central Committee on accelerating the construction of a powerful country in science and technology and realizing high-level scientific and technological self-reliance, adhere to the overall leadership of the party, adhere to the "four orientations", persist in self-reliance, persist in carrying forward the spirit of scientists, fully implement the law on scientific and technological progress, and guarantee the construction of a powerful country in science and technology with the rule of law. It is necessary to adhere to the problem-oriented and result-oriented orientation, give full play to the advantages of the new national system, strengthen the national strategic scientific and technological strength, strengthen basic research, deepen the reform of the scientific and technological system and mechanism, improve supporting regulations and institutional measures, and find out problems, fill shortcomings, strengths and weaknesses, promote the comprehensive and effective implementation of the scientific and technological progress law, and further improve the level of legalization of scientific and technological innovation. It is necessary to carry out law enforcement inspection in a solid manner, strengthen study and research, be strict in style and discipline, go deep into the grassroots and practice, fully understand the implementation of the law, find outstanding and typical problems, study and analyze the reasons, make full use of law enforcement inspection to strengthen the publicity of law popularization, and give full play to the supervisory function of the National People’s Congress.

  During the meeting, Han Jun pointed out that in recent years, Anhui has thoroughly studied and implemented the important guiding spirit of the important speech of the Supreme Leader General Secretary on scientific and technological innovation, accelerated the implementation of the innovation-driven development strategy, comprehensively implemented the scientific and technological progress law, strengthened the national strategic scientific and technological strength, strengthened key core technology research, improved the application level of scientific and technological innovation, accelerated the integration and development of scientific and technological industries, deepened the reform of scientific and technological system and mechanism, strived to create an influential source of scientific and technological innovation, and injected strong momentum into high-quality economic and social development. In the next step, we will take the construction of high-level innovative provinces as the banner, make every effort to build a high-level innovative province and a strong province of science and technology, and contribute to the country’s high-level scientific and technological self-reliance. I hope that the National People’s Congress will continue to care for and support Anhui and help us do our work better.

  Luo Shugang, chairman of the NPC Education, Culture, Health and Welfare Committee, Hou Jianguo and Tian Xuejun, vice-chairmen of the NPC Education, Culture, Health and Welfare Committee, Ma Xu, NPC deputies Liu Jizhong and Yu Shuhong attended the law enforcement inspection. Provincial leaders Zhang Yunsheng, Zhang Hongwen and Wang Cuifeng, and Party Secretary Shu Gequn of China University of Science and Technology accompanied the inspection or participated in relevant activities.

The market supervision complaint telephone number will be unified to 12315 next year.

  (Reporter Lin Lishuang) Yesterday, official website, General Administration of Market Supervision, issued the Opinions of General Administration of Market Supervision on Integrating and Building 12315 Administrative Law Enforcement System to Better Serve Market Supervision and Law Enforcement. Before the end of 2020, the original complaint reporting hotlines for industry and commerce, quality inspection, food and drug, price and intellectual property rights, namely, 12315, 12365, 12331, 12358 and 12330, will be unified into 12315 hotline, and the market supervision complaint reporting service will be provided with one number of 12315.

  According to the deployment of opinions, by the end of 2020, a unified, authoritative and efficient 12315 administrative law enforcement system will be basically established.

  The integration and construction work is divided into two stages, with 2019 as the transition period, which mainly realizes "No.1 external, multi-line parallel, centralized answering, undertaking at all levels, and handling by departments according to their responsibilities"; Upgrade the national 12315 platform, and initially unify the entrance of market supervision complaints and reports; Based on the national 12315 platform, we develop and deploy the user terminal of the wiring staff, and realize the real-time collection and dynamic management of the 12315 hotline data on the national 12315 platform.

  In 2020, relying on the national 12315 platform, we will gradually improve the hotline and platform for receiving complaints and reports from market supervision departments, build a unified national 12315 administrative law enforcement system, realize the working mechanism of "No.1 external service, centralized management, facilitating the people and enterprises, and efficient law enforcement", and build a unified market supervision and law enforcement system to maintain a relaxed and convenient access environment, a fair and orderly competition environment, and a safe and secure consumption environment.

The latest response from Shen Teng, who was seriously ill, came: Everything is fine!

1905 movie network news Recently, it has been widely rumored on the Internet that due to serious illness, there are still many operations to be done, and it is about to retire, which has aroused everyone’s concern. On the evening of April 28th, Shen Teng sent a message on social media to respond:Everything is fine recently. Thank you for your concern.


Earlier, some netizens met Shen Teng in Japan and shared photos of Reuters on social platforms. Subsequently, Shen Teng suffered from cervical spondylosis and lumbar spondylosis, and the rumor that he was going to Japan for surgery was rampant. Finally, it evolved into Shen Teng, which was seriously ill and was about to retire, which made netizens very worried. Fortunately, Shen Teng responded in time. In addition to saying that everything is fine, he also sent a few pictures to reveal himself.I am watching the new musical The Awakeing Age of our company, and I recommend it to you. I wish you a happy holiday. ".

The Korean remake of Rene Liu’s Later Us was released in 2023.

1905 movie network news  On June 15th, SHOWBOX, a Korean film distribution company, announced a remake of the film directed and starring, which is expected to be released in 2023.


It was released in China on April 28, 2018. After the release, it won the single-day box office champion for 12 consecutive days, becoming the box office champion in May 1st in 2018, and finally won 1.36 billion box office. After landing in South Korea in 2018, "Later Us" was deeply loved by local audiences, and scored more than nine points in Korean movie portals.

Rene Liu’s version of Later Us tells the story that college student Lin Jianqing and fellow countryman Fang Xiaoxiao met on the train in Spring Festival travel rush, and started the struggle life of drifting north together. They experienced love, breakup and miss, and they met again ten years later.



The front desk tests the water first: what about the AI that has launched many generative AI programs and knows more about Chinese culture?

  It is generally believed in the industry that if 2023 is a "wild year" for generative artificial intelligence technology, then 2024 is expected to be the "first year" for the great development of artificial intelligence applications. With the development of AI big model and various text generation, Wensheng pictures and Wensheng video tools all the way this year, the global media industry will also usher in all-round changes in the way of content production, dissemination and consumption. The revolutionary breakthrough of technology presents the creator with a "magic pen". How should the media seize the opportunity to become a "good horse" who makes good use of this wonderful pen?

  On February 26th, China’s first Wensheng video AI series was produced by the Central Radio and Television General Station.200 episodesThe animated film "Ode to a Thousand Years" was launched. The first AI mini-drama "The Myth of China" and the first AI translated English series of micro-documentaries "The Story and the Story" were also released.This is a set of concrete practices for the Headquarters to actively explore the innovative application of generative artificial intelligence technology in the media field, seize a new round of scientific and technological revolution and industrial transformation, and strive to seize the commanding heights of future industrial competition to empower the cultural industry and international communication.

  With the empowerment of AI, the future of the media industry has come. How to tell Chinese cultural stories well through generative AI? How to make the new quality productivity become the biggest increment of the high quality development of the main station? Let’s start with a series of AI practices led by the reception desk.

  AI big model with China aesthetic.

  Let it sing, and ask for its friendly voice. The communication between people begins with the communication of language. Similarly, the communication between creators and AI has to go through the communication process of "meeting friends with literature".

  In July 2023, the Headquarters and Shanghai Artificial Intelligence Laboratory released the "CCTV Listening Media Model", which was first applied to the creation of Ode to a Thousand Years.In the first season of Ode to a Thousand Years, the latest technological achievements such as controllable image generation, dynamic character generation and literary video were comprehensively used.Six well-known Tang poems, such as Ode to Goose, Crossing the Old Man’s Village and a farewell to meng haoran on his way to yangzhou of the Yellow Crane Tower, were transformed into beautiful national animation.

  The program creation team uses a large number of Chinese paintings and ancient poems as training materials to communicate with the AI ? ? model. After countless collisions between artistic creation language and code language,"CCTV listening to the media model" has a unique style and strength — — China’s aesthetics.It can accurately understand the traditional cultural words such as "national style, Tang Dynasty, freehand brushwork and meticulous painting", and generate fine art materials such as meticulous painting and ink painting, so as to reproduce the artistic conception and beauty of poetry to the maximum extent.

  The ratings of the first six episodes of Ode to a Thousand Years’ Poetry ranked first among all the cartoons on the satellite channel in China, reaching a total audience of 94.413 million people., the central video client’s live viewing volume reached 13.182 million person-times, and Weibo’s topic reading volume totaled 92.814 million person-times. Hundreds of mainstream media at home and abroad, including VOA, pay attention to the innovative practice of the reception desk. Many experts and scholars in the fields of science and technology, media and education expressed their support and affirmation.

  Many netizens commented that "AI has shaped a new mode of production, and Ode to a Thousand Years of Poetry has opened up the imagination of the industry." "When the AI ? ? big model meets the oriental aesthetics, China’s poetry is really ‘ Live ’ Get up "and" enter the smart primary and secondary school platform early, which is convenient for teachers and students to use "… …

  AI can also activate the imagination of more cultures. "Ode to a Thousand Years" has just started broadcasting. On February 29th, the artificial intelligence studio of the General Station and the Tsinghua University Yuan Universe Culture Laboratory jointly produced the "China Myth Series Mini-short Drama" and "Mending the Sky", which was released to creatively interpret the enduring code of Chinese civilization contained in myths and legends.This is the first full-process mini-drama of AI in China. Art, camera, video, dubbing and soundtrack are all completed by AI, which is another pioneering practice for the film and television application of AI technology.

  The key to Wensheng video is "text". Long-term infiltration in Chinese culture, repeated training and deep learning, the research and development of "CCTV listening to media model" is becoming more and more mature, the future program production cycle will be further shortened, and the fineness of works will be continuously upgraded. More and more "understanding" AI partners can not only save time and effort in film and television animation production, game development and advertising design, but also accelerate the development process of mature application of Wensheng video, business model expansion and overseas spread.

  How does AI improve the efficiency of international communication?

  The application practice of AI in many international communication scenes at the main station shows that AI-assisted production can not only greatly improve the efficiency of multi-language conversion and multi-platform distribution, but also realize authentic and loving cross-cultural interaction under the escort of man-machine collaboration.

  Question 1:

  Suppose you are an artificial intelligence. Today’s job is to translate a documentary in English. When a dragon talks seriously about how to "fine raise dragons" and talks about "Nagada in Northeast China" with his own accent, how should you deal with it?

  A: Note that to explain loong’s "ins and outs" clearly in a foreign language, you should not only translate it accurately and rigorously, but also speak it erudite and lovely.

  This documentary, named "The Story", is a series of loong-themed micro-documentaries translated by the Headquarters with the full AI process empowerment, and will be launched soon.The film effectively explores the efficient application scenario of the whole process of film and television translation of AI. Using AI technology, the whole translation process from voice recognition, text translation, voice cloning to track-splitting replacement has been completed, which highly restored the style of the original Chinese film and the "character dragon design" of narration.The accuracy of translation is ensured by man-machine cooperation, which greatly improves the efficiency of translation.

  In addition to the English version, the Spanish, Portuguese, Indonesian, Filipino and other versions of The Story, the multilingual version of Ode to a Thousand Years ago and other excellent programs have fully utilized the independent AI technology of the reception desk to assist in the translation. On March 10th, the English and Spanish versions of Ode to a Thousand Years’ Poetry were officially released on CGTN. At the same time, multilingual film and television translation will be included in the training plan of CCTV Listening to Media Model, which will help the construction of the national multilingual film and television translation base of the General Station and effectively improve the international communication efficiency of Chinese film and television culture.

  Question 2:

  There is a group of news reports that need to be translated in multiple languages and distributed overseas in the shortest time. Is there any way to quickly generate multilingual and batch video products?

  A: Yes.The main station makes full use of AI technology, and realizes the geometric progression growth of news output and broadcast quantity through the form of multi-language superposition and multi-platform distribution.For example, in a short period of one week, the series of English reports of Opportunity China: A First-line Economic Observation was transformed into nearly 100 multilingual video products in 10 languages, including Spain, France, Albania, Russia, Germany and Portugal, and broadcast on overseas platforms, which strongly refuted the so-called "China economic summit theory" in the United States and the West.

  These products have clear and bright pictures and real and natural sounds, which bring surprises to overseas netizens. A Russian netizen left a message: "I am also surprised that this Chinese speaks Russian without any accent. It turned out to be AI, which is really awesome!"

  It is not only the reported multilingual conversion, but also the AI virtual digital avatars of several CGTN hosts. The production mode of generating video through manuscript input saves the real-life recording link, shortens the shooting and material export work that originally took up to 2 hours to only 5 minutes, and greatly improves the upper limit of single-person single-day video output.

How does the AI track run steadily and accelerate?

  There is a view that the development of artificial intelligence, especially the exponential growth of generative AI, has shortened the unit of measurement of technological change from years and months to days, and may even be calculated in hours and minutes in the future. If you don’t advance, you will retreat, and if you advance slowly, you will retreat. All in or wait and see? For the media industry, it is more critical to find a way to increase productivity through technological innovation.

  How does the media industry run out of "acceleration" on the AI ? ? track? In the development and application of generative AI technology, there are two main development concepts that the main station has always adhered to.

  On the one hand, we should insist on original research, and strive to build an internationally leading model of Wensheng video with China cultural characteristics.Compared with Sora’s vivid visual effects, the AI animation of programs such as Ode to a Thousand Years ago has some problems, such as blurred background and insufficient coherence of characters’ actions, which shows that there is still a certain gap between the video generation model independently developed by China and the world’s advanced technology. However, at present, the Chinese corpus accounts for only 1.3% of the global large-scale model data training set, and the characteristics of China are obviously insufficient. Facts show that insisting on original research is the fundamental to promote the development of independent general artificial intelligence in China.

  In 2023, the Headquarters and Shanghai Artificial Intelligence Laboratory jointly established the "China Large Model Corpus Database Alliance".On the understanding and expression of Chinese culture, and the integration with the actual production process created by the media, the AI practice led by the General Desk has unique China aesthetic and Chinese cultural characteristics.

  The main station has a rich and standardized audio-visual corpus such as China Audio-visual Archive, and all materials have been tagged, which is also the largest Chinese audio-visual corpus in the world.Training with the massive high-quality audio-visual data and professional media creation knowledge of the main station, the model is expected to grow rapidly in continuous actual combat and embark on a differentiated road of China’s technological development.

  On the other hand, to do a good job in platform construction, we should promote the integration of "Industry-University-Research" and continuously optimize the safe and reliable AIGC technology platform.The core of big model breakthrough lies in algorithm, computing power and data. The Headquarters will work with Shanghai Artificial Intelligence Laboratory to build an independent and controllable domestic intelligent computing platform, and further promote the newly established large-scale model research and development community and artificial intelligence studio construction. Linking the upstream and downstream of the industrial chain, the first-class scientific research institutions, universities and enterprises in the United Nations will cooperate in the fields of scientific research, demand application, safe development and industrial ecology.

  Since the establishment of the main station, the whole stage has always maintained a state of being in danger, breaking through difficulties and seizing opportunities. Beginning in 2019, the head office leaders visited Shanghai Jiaotong University and other institutions to discuss the high-quality development of the artificial intelligence empowerment head office and set up relevant cooperative research institutions. After the Sora Wensheng video appeared, the leader of the main station asked the whole station to pay close attention to it and keep a close eye on it to prevent a complete defeat overnight.Artificial intelligence does not make creativity "fall from the sky", but opens up new application scenarios for "golden ideas" from all walks of life, providing innovative infrastructure and auxiliary capabilities.

  After several years of practice, the Headquarters has continuously deepened the development strategy of "5G+4K/8K+AI", and at the same time vigorously promoted the innovation of media technology, transformed the new quality productivity into more refreshing quality programs. A series of practical achievements about generative AI made by the Headquarters are not a temporary follow-up "early adopters", but a series of "products made by the Headquarters" and "golden business cards" of Chinese culture. How will the AI road of the main station continue to break through the boundaries of media technology and create new imagination and fresh experience about Chinese culture for the global audience? I believe there are more scenic spots ahead.

The first batch of national parks in China was formally established Northeast Tiger and Leopard National Park | The largest settlement and breeding area of wild Siberian tiger and leopard in China.

CCTV News:Northeast Tiger and Leopard National Park, which spans Jilin and Heilongjiang provinces, is located in the center of Asian temperate coniferous and broadleaved mixed forest ecosystem, adjacent to Russia and North Korea. It is the largest and only settlement and breeding area of wild Siberian tiger and leopard population with breeding families in China. With various vegetation types and relatively complete ecological structure, the park is a typical representative of temperate forest ecosystem and a model of cross-border cooperation and protection.

It is understood that since the pilot of the Northeast Tiger and Leopard National Park in August 2017, the ecosystem in the pilot area has been protected, restored and managed as a whole, and the ecosystem with tigers and leopards as its flagship species has shown a good recovery trend, embarking on a new path in which important natural resource assets across provincial administrative regions are directly exercised by the central government. According to the latest data from the Northeast Tiger and Leopard National Park Administration, the number of wild Amur tigers and Amur leopards in the Northeast Tiger and Leopard National Park has also increased from 27 and 42 at the beginning of the pilot in 2017 to 50 and 60 respectively, and more than 10 newly bred cubs and more than 7 cubs have been monitored.

The FDA’s annual inventory came, and 37 innovative drugs were approved! The domestic new drug "going out to sea" was a success, and these two domestic pharmaceutical companies lit up.

Recently, the FDA released the annual report on new drugs in 2022. The data shows that the FDA approved 37 innovative drugs to be listed last year, with the number reaching a new low of nearly six years, of which nearly 50% have been listed in China or are in the review stage. The FDA promotes and speeds up the evaluation of new drugs in various ways through "multi-pronged approach". In 2022, a number of domestic innovative drugs "went out to sea" to break through the FDA, and the results were "mixed". Two domestic innovative drugs were approved by the FDA and four hit a wall.

Figure 1: Number of new drugs approved by FDA in recent ten years

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Source: FDA2022 Annual Report on New Drugs (New Drug Therapy Approvals 2022).

37 innovative drugs were approved, and 18 accelerated the entry into the China market.

Recently, the Center for Drug Evaluation and Research (CDER) of FDA released the annual report of new drugs in 2022. In 2022, the FDA approved the listing of 37 innovative drugs, with the number reaching a new low of nearly six years. Among the approved innovative drugs, 20 (54%) belong to "first-in-class" innovative drugs, and 20 (54%) are drugs for rare diseases.

As the benchmark of global pharmaceutical supervision, FDA has approved 28 new drugs (76%) in the first round, and 25 (68%) in the United States before other countries.

In 2022, FDA promoted and accelerated the evaluation of new drugs in various ways through "multi-pronged approach". Twelve (32%) were identified as fast-track, 13 (35%) were identified as breakthrough therapeutic drugs, 21 (57%) were identified as priority review, and 6 (16%) were accelerated for approval. CDER used one or more accelerated development and review methods for 24 (65%) of all new drugs approved in 2022.

Table 1: Innovative Drugs Approved by FDA in 2022

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29821674084710717

9221674084710820

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Source: FDA website, intranet database.

In recent years, more and more attention has been paid to innovative drugs in China. In 2022, innovative drugs approved in the United States are also running into the China market at "China speed" to solve the unmet health needs of more China patients. According to statistics, at present, 18 (49%) innovative drugs are at the stage of clinical application and above in China. Among them, four innovative drugs, namely, abcixinib, voronoxan, benvimod and pessolizumab, have been approved for marketing, while otconazole and deuterium colexitinib are in the application stage, while nine innovative drugs are in clinical phase III, one in clinical phase I and two in clinical application.

Table 2: Research and Development of Innovative Drugs in China

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Source: Minenet database

Two domestic innovative drugs "went to sea" successfully, and legendary creatures actively expanded their territory.

In 2022, a number of domestic innovative drugs "went out to sea" broke through the FDA, and Sidakio Orense and Benvimod returned gratifying news and were successfully approved for listing.

On February 28th, 2022, the BCMA CAR-T drug Cedactylosin developed by Kingsley’s Legendary Biology was approved by FDA for the treatment of relapsed or refractory multiple myeloma. Cedactylosin became the first cell therapy product approved by FDA in China and the second CAR-T cell immunotherapy approved for BCMA in the world. This is a beautiful "turnaround" after the FDA announced the tightening of China’s listing policy for innovative drugs, which means that China has officially entered the world’s first-line position in the field of cell therapy.

After the successful listing in the United States, Sida Chiolense also extended its listing territory to the European Union and Japan in 2022. In May, 2022, the European Commission (EC) has granted conditional marketing permission to Cedactylosin for the treatment of adult patients with relapsed or refractory multiple myeloma who have received at least three treatments in the past, including immunomodulatory drugs, proteasome inhibitors and anti-CD38 antibodies, and the last treatment showed disease progression. In September, 2022, the Japanese Ministry of Health, Labor and Welfare approved Cedactylosin for the treatment of adult patients with recurrent or refractory multiple myeloma. At present, in China, Sida Chiolense is in the stage of applying for listing.

Figure 2: Global R&D progress of Sida Chiolense.

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77311674084711093

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On May 24th, 2022, Dermavant Sciences announced that the FDA had approved the marketing of VTAMA (Benvimod, 1%) cream for the local treatment of adult plaque psoriasis. Benvimod, developed by Tianji Medicine, a domestic enterprise, is the first-in-class new drug with independent intellectual property rights.

In 2012, GSK obtained the overseas development right of Benvimod with a down payment of nearly $200 million. In July 2018, GSK announced that it would sell the overseas development right of Benvimod to Dermavant for $330 million.

As early as May 2019, Benvimod was approved to be listed in China as a "Class 1 new drug" for adults with mild to moderate stability psoriasis vulgaris suitable for local treatment. So far, benvimod is the first innovative drug approved by the FDA after it was approved for marketing in China.

Figure 3: Global listing of Benvimod

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The road to "going out to sea" is not smooth. Cinda Bio and Junshi Bio … find another way out.

The road to "going out to sea" was not smooth sailing. In 2022, the innovative drugs of Cinda Bio, Junshi Bio, Hutchison Whampoa and Baekje Shenzhou all submitted their applications for listing in the FDA, but they were rejected by the FDA one after another.

Table 3: Drugs not approved by FDA in 2022

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In March, 2022, Cinda Bio announced that FDA refused to approve the listing application of new drugs for the first-line treatment of patients with non-squamous non-small cell lung cancer, including cindilizumab combined with pemetrexed and platinum chemotherapy. In its reply to Cinda Bio, FDA pointed out that the related product trials of Cinda Bio were only conducted in China, not global multi-center clinical trials, and the results were not applicable to patients in the United States due to the nature of a single country.

In May, 2022, Hutchison announced that the US FDA had not approved the application of Suo Fan tinib for the marketing of new drugs for the treatment of pancreatic and non-pancreatic neuroendocrine tumors. The reason for FDA’s rejection of Hutchison is similar to Cinda Bio’s. It thinks that the data package of Hutchison based on two successful China Phase III studies and an American bridging study is not enough to support the drug’s approval in the United States, and more international multi-center clinical trials representing American patients need to be included to support the approval in the United States.

In the same month, Junshi Bio’s application for the marketing of PD-1 antibody Treprilizumab received a complete reply from FDA, requesting a quality control process change. This process change was rejected because the facilities could not be inspected on site due to travel restrictions during COVID-19.

In July, 2022, Baekje Shenzhou announced that the FDA of the United States could not complete the required on-site verification work in China as scheduled due to travel restrictions related to the COVID-19 epidemic, so it would extend the completion time of the target review of the application for the new drug listing license for second-line esophageal squamous cell carcinoma. However, its partner Novartis revealed in the quarterly report that it had cancelled the listing application for the treatment of non-small cell lung cancer with tierellizumab in the United States.

In the face of the "ruthless" rejection of the FDA, Junshi Bio quickly made adjustment measures and resubmitted the application for the listing of Trepril monoclonal antibody to the US FDA. The FDA has set the date of PDUFA as December 23rd, 2022. Trepril monoclonal antibody is still in the approval stage, and there is no clear result. Hutchison Whampoa said that it is working with the FDA to evaluate the next step. Baekje Shenzhou is rumored to move to Europe, and it is expected that it will submit its first listing application in the EU in 2023. Cinda Bio announced at the end of the year that it had recovered the overseas rights and interests of Cindilizumab from its partner Lilly Pharmaceutical.

There are many cases of domestic innovative drugs failing to go to sea. On the one hand, FDA has high requirements for domestic pharmaceutical companies’ products going to sea. According to the FDA’s previous requirements for Cinda Bio, if the new PD-1 wants to be listed in the United States, it needs to compete with the existing standard therapies. And drug K has been approved for dozens of indications in the United States, and products with the same indications have to cross the mountain of drug K if they want to be approved. On the other hand, at present, how to conduct clinical trials of domestic innovative drugs overseas is still in the exploratory stage. These failed cases essentially reflect the doubts of foreign mature markets on the quality of clinical trials in China.

tag

2022 has passed, and the innovative drugs approved by FDA are the direction of global innovative drug research and development trends, leading the way for innovative pharmaceutical companies. For domestic innovative pharmaceutical companies, if they want their products to go abroad, there is no doubt that they should sum up their previous experience in innovating drugs in the FDA, always pay attention to the changes in the clinical pattern, and keep in touch with the FDA for clinical design. At the same time, we should improve our products from many dimensions, such as reflecting the innovation of products, meeting unmet clinical needs, improving drug accessibility, improving technology, selecting indications, and improving safety and efficacy.

Source: Minenet comprehensive database.

This article is an original manuscript, please indicate the source and author, otherwise the tort liability will be investigated.

Tales of mainland Olympic athletes visiting Hong Kong

  Xinhua News Agency, Beijing, December 1st (Reporter Pan Yi, Wang Yao, Wei Hua) A highly anticipated delegation of mainland Olympic athletes will arrive in Hong Kong on December 3rd for a three-day exchange activity. A total of 29 athletes from track and field, swimming, diving, weightlifting, gymnastics, trampoline, rowing, kayaking, cycling, fencing, table tennis and badminton participated in the Tokyo Olympic Games. The following are biographies (in order of projects):

  "Asian Flying Man": Su Bingtian

  In the men’s 100-meter semi-final of the Tokyo Olympic Games, Su Bingtian broke the Asian record at a speed of 9.83 seconds, ranking first in the semi-final and advancing to the final, becoming the first Chinese to stand on the runway of the Olympic men’s "flying man" final. After that, Su Bingtian won the sixth place in the final in 9.98 seconds, setting a new record. Running for 10 seconds twice in such a short time is a miracle in Asia.

  Women’s shot put champion: Gong Lixiao.

  Gong Lixiao has been practicing shot put for 21 years, and she is the leader of women’s shot put in China. At the Tokyo Olympic Games, Gong Lixiao, as the "four-dynasty veteran" of the Olympic Games, wrote the "Veteran Legend". In the final, she refreshed her personal best again and again, and finally won the championship with 20 meters 58. This is also the first gold medal in field events in the history of China Olympic Games.

  Women Javelin Champion: Liu Shiying

  At the Tokyo Olympic Games, Liu Shiying won the women’s javelin gold medal with a score of 66.34 meters, becoming the first person in China and even Asia to win the Olympic javelin gold medal. At the critical moment, strength plus a stable mentality played a decisive role.

  Women’s 4X200 freestyle relay champions: Yang Junxuan and Tang Muhan.

  In the women’s 4X200 freestyle relay final of Tokyo Olympic Games, Yang Junxuan and Tang Muhan cooperated with Zhang Yufei and Li Bingjie to win the championship and break the world record with 7 minutes 40.33 seconds.

  Yang Junxuan swam first, giving China a lead. Tang Muhan, the second best player, extended China’s lead from 0.14 seconds when he received the bat to 0.45 seconds when he handed it over.

  Yang Junxuan is quiet and likes painting and calligraphy. She is a "talented girl" in the swimming team. On holidays, the gifts she often gives are hand-painted paintings, couplets and blessings.

  Diving Men’s Double Single 3m Slab Double Champion: Xie Sicai

  At the Tokyo Olympic Games, Xie Sicai won the men’s 3m springboard synchronized gold medal with Wang Zongyuan, and then defeated Wang Zongyuan to win the men’s 3m springboard gold medal. Wang Zongyuan won the silver medal. Xie Sicai also became the second athlete to win the men’s 3m springboard "double champion" in a single Olympic Games after Xiong Ni, the diving prince.

  Xie Sizhen suffered a serious ankle fracture in 2014, and two steel nails and a rivet were implanted in the injury. The doctor warned him that he could no longer practice diving. However, he refused to surrender to fate.

  Diving men’s synchronized 3m springboard champion: Wang Zongyuan.

  In Tokyo, Wang Zongyuan, who played in the Olympic Games for the first time, won the gold medal in the men’s synchronized 3m springboard with Xie Sichai, which was the only event that China’s diving "dream team" missed in Rio Olympic Games. Wang Zongyuan and Xie Sichai succeeded in making up for this regret.

  Women’s 49 kg weightlifting champion: Hou Zhihui

  Hou Zhihui won the gold medal with a total score of 210kg in the women’s 49kg weightlifting competition in Tokyo Olympic Games. The coach’s evaluation of her is "high concentration and good coordination, and she is an athlete who trains with her brain".

  Women’s weightlifting 87kg champion: Wang Zhouyu

  The women’s 87 kg class is a new level set by the International Federation of Weightlifting in 2018. Wang Zhouyu rose from the 76 kg class. It is not everyone’s wish to gain 10 kg.

  Women’s weightlifting champion over 87kg: Li Wenwen.

  Li Wenwen is cheerful, and once became popular on the Internet because of a small video of sleeping on the floor. She once joked: "Every fat girl has her own dream."

  Weightlifting men’s 61kg champion: Li Fabin

  In the national team with many experts, Li Fabin didn’t get the chance to participate in the Olympic Games until he was nearly 30 years old. In the final in Tokyo, Li Fabin’s "Golden Rooster Independence" shocked the world.

  Men’s 67 kg weightlifting champion: Chen Lijun

  In the final of the Tokyo Olympic Games, due to the poor performance of snatch, the Huli Army was 11 kilograms behind its Colombian opponent. However, he only used one of the last two clean and jerk opportunities to reverse the turnaround and successfully lifted 187 kilograms, an astonishing 12 kilograms more than his last attempt.

  Men’s 73kg weightlifting champion: Shi Zhiyong.

  Won the men’s weightlifting 73kg class in Tokyo Olympic Games and broke the world record in total score. At the age of 11, Shi Zhiyong went to Ningbo alone with a woven bag, and later became the 69kg champion of the Rio Olympic Games. After the Rio Olympic Games, the International Weightlifting Federation adjusted the weightlifting level, and he was upgraded to 73kg, but it didn’t beat Shi Zhiyong. Since 2018, he has continuously set a world record, and he stands out in the 73 kg class.

  Men’s weightlifting 81kg champion: Lv Xiaojun.

  Lv Xiaojun is the weightlifter who won the most Olympic medals in China and became the oldest Olympic champion in weightlifting history at the age of 37. This is also his second Olympic gold medal in his life after winning the gold medal at the London Olympics.

  The champion of men’s gymnastics parallel bars: Zou Jingyuan

  Zou Jingyuan’s parallel bars strength can be described as a ride in the current men’s gymnastics world. In the parallel bars final of the Tokyo Olympic Games, his almost perfect movements left no chance for his opponents to surpass him.

  Men’s Gymnastics Rings Champion: Liu Yang.

  Liu Yang’s rings are as beautiful as a textbook. At the Tokyo Olympic Games, his "Wang Zhi’s contempt" for turning his neck on the rings was described by the official Twitter of the International Olympic Committee as: "How can someone look so cool while competing on the rings!"

  Women trampoline champion: Zhu Xueying

  On August 28th, 2021, Zhu Xueying donated her Olympic gold medal and award-winning clothing to Tianjin Sports Museum, becoming the first athlete to donate the gold medal of Tokyo Olympic Games. She said, "It is more meaningful to display the Olympic gold medals in the museum than at home. I look forward to more audiences entering the exhibition hall, feeling the Olympic spirit, feeling the charm of sports culture and drawing on the strength of forging ahead. "

  Women’s rowing quadruple sculls champions: Cui Xiaotong, Lu Yang, Zhang Ling and Chen Yunxia.

  Cui Xiaotong, Zhang Ling, Chen Yunxia and Lu Yang worked closely together to lead the way in the women’s rowing quadruple sculls final of Tokyo Olympic Games, winning the championship with the world’s best result of 6: 05.13.

  Cui Xiaotong, who has an excellent sense of water, as the No.4 rower, has well controlled the rowing rhythm of the four people. Cui Xiaotong, who used to practice single oar, only changed to practice double oars three years ago, but she trained hard and made rapid progress. She often said, "If you don’t torture yourself in training, you will be tortured by your opponent in the game."

  As the No.2 rower, Zhang Ling is the driving force of the whole boat. As the No.1 rower with the highest technical requirements, Chen Yunxia kept the balance of the whole boat well. She changed to rowing after practicing track and field for five years, and her physical fitness is outstanding. Lu Yang, the No.3 rower, plays the role of all-round assistant, on the one hand, helping the No.4 rower to control the rhythm, on the other hand, helping the No.2 rower to become the strength support in the rowing process.

  Still water women’s 500m synchronized rowing champion: Xu Shixiao and Sun Mengya.

  In the final of the still water women’s double rowing in Tokyo Olympic Games, Xu Shixiao and Sun Mengya teamed up to win the championship with the best performance in the Olympic Games, winning the first Olympic gold medal for the China women’s canoeing team in history.

  Xu Shixiao, who became famous at a young age, has experienced injuries, retirement and comeback. Xu Shixiao said that kayaking is a kind of feeling for her. Although there are losses and valleys in the process, these eventually become the driving force on her way forward.

  Sun Mengya, who entered the sports school only one year ago, almost gave up kayaking because of her father’s injury, but she finally persisted.

  Champion of track cycling women’s team racing: Zhong Angel

  At the Rio Olympic Games five years ago, Zhong Angel partnered with gong jinjie to win the gold medal in this event, achieving the breakthrough of "zero" in China’s cycling Olympic gold medal. At the Tokyo Olympic Games, Angel Zhong and Bao Shanju broke the world record of women’s team racing held by China in 31.804 seconds, and defeated the German team in the final, winning the second cycling gold medal for China in Olympic history.

  Women’s individual epee champion: Sun Yiwen

  At the Tokyo Olympic Games, Sun Yiwen won the first women’s weightlifting individual gold medal in the history of China Olympic Games in the final overtime, becoming the first China fencer to win individual medals in two consecutive Olympic Games.

  Table tennis men’s singles and men’s team champion: Malone

  Malone is the first winner of men’s double slam and full slam in the history of world table tennis. Tokyo Olympic Games has become a stage for Malone to constantly refresh history. Beating the world number one Fan Zhendong to win the gold medal in men’s singles, Malone became the first defending man in the history of Olympic table tennis and the player with the most world titles in the history of table tennis.

  Table tennis men’s team champion: Xu Xin.

  Left-handed straight, unique play. In October this year, at the Asian Table Tennis Federation Congress held in Doha, Qatar, Xu Xin was elected as the vice chairman of the Asian Table Tennis Federation.

  Badminton mixed doubles champions: Wang Yilu and Huang Dongping

  In the badminton mixed doubles final of Tokyo Olympic Games, Wang Yiliu’s partner Huang Dongping, who participated in the Olympic Games for the first time, defeated teammate and top seed Zheng Siwei/Huang Yaqiong 2-1.

  Wang Yilu has outstanding physical fitness and firm will. He often says: "What people fear most is that they have no goal, just like salted fish. With clear goals, happiness will increase. "

  Huang Dongping often reminds himself: "No matter whether there is harvest or not, it is definitely right to pay."

Shaanxi Higher People’s Court filed a case for review. The complainant has been released from prison for raping and killing a young girl 25 years ago.

Lu Tianhui (first from the right) and his complaint agent Deng Xueping (middle) took a group photo with the interviewee.

  Lu Tianhui, a man from Hanzhong, Shaanxi Province, was sentenced to life imprisonment because he was found to be the murderer of a young girl case 25 years ago. After commutation, he was released in January this year after more than 24 years in prison.

  After being released from prison, 55-year-old Lu Tianhui complained that he was not the murderer. On October 16th, The Paper learned from the relevant staff of Shaanxi Higher People’s Court that the court has initiated a case review of Lu Tianhui’s case, and it is not convenient to disclose the latest progress of the review.

  Many years ago, when the case was opened in the first instance, Lu Tianhui, who had made a guilty confession to the police, retracted his confession in court. Before the verdict was pronounced in the first instance, Hanzhong Intermediate People’s Court sent the case back for supplementary investigation four times, demanding to eliminate multiple doubts. The fourth decision on returning the investigation stated that "after many times of returning the investigation, the facts of this case were unclear and the evidence was insufficient", and there were many doubts and there was no statutory case.

  The police issued a number of "Notes" in this regard, and the case was finally decided. On May 21, 1999, after Lu Tianhui was detained for more than four years, Hanzhong Intermediate People’s Court pronounced the sentence in the first instance, and found Lu Tianhui guilty of intentional homicide and rape of a young girl, and sentenced him to life imprisonment. After Lu Tianhui appealed, the Shaanxi High Court made a final ruling in September of the same year and upheld the original judgment.

  The Paper noted that in the judgment of the first instance, the defender believed that Lu Tianhui was found guilty of adultery and murder of a young girl, based on indirect evidence such as on-site inquest and criminal scientific and technical appraisal, and suggested that the court should impose appropriate punishment. Hanzhong Intermediate People’s Court held that "the defender’s defense opinions can be adopted."

  Deng Xueping, Lu Tianhui’s appeal attorney, told The Paper after consulting the case file that there were many doubts in the case, and the most important thing was that the key evidence for finalizing the case was only blood group identification, and the result was not exclusive.

  According to the file data, in June 2004, due to Lu Tianhui’s complaint, Hanzhong Intermediate People’s Court filed a case for review. Yajun Gao, then the director of Sujiaying Police Station who handled the case, said in a telephone inquiry during the review of Hanzhong Intermediate People’s Court that the important evidence of Lu Tianhui’s case was blood, "blood proved that he killed the little girl". Five months after the investigation, Hanzhong Intermediate People’s Court decided to reject the complaint.

  The police locked the suspect by blood type identification.

  At 10 o’clock on the morning of September 4, 1994, the police of Hedongdian Police Station in Hantai District, Hanzhong City, Shaanxi Province received a report from the masses that a woman’s body was found in a paddy field by two groups of villagers in Hongqi Village, Hedongdian Town one day ago. When it was found, it was highly decomposed, leaving only the skeleton.

  The villagers remembered that more than 20 days ago, Lu Cun, a villager in the neighboring Quluying village, reported to the police that her only daughter Lu Li (a pseudonym) was missing. Lu Cun said in the missing report that on August 8, 1994, he and his wife went out to work, leaving his daughter to write at home. When he came home at noon, his daughter was gone. Until seven o’clock that night, Lu Li still didn’t go home. He and his wife began to look around.

  After the family members identified the clothes worn by the bones and compared them with the blood type, the police determined that the deceased was 10-year-old Lu Li. The Paper noticed that there was no DNA identification report on the identity of the female corpse and other evidence in the existing case files, and it was not mentioned in the list of evidence listed in the judgment.

  The autopsy report showed that the bone color of Luli’s right eyebrow arch, under the nasal bone and pubic symphysis became darker, which proved that she had suffered blunt injury before her death, but the cause of death could not be determined because of the high corruption of the body.

  The police once investigated many male villagers in the same village, but it was fruitless. Lu Tianhui, a young man living alone in the straw house of Changtan Forest Farm on the bank of Baohe River, caught the attention of the case handlers. The straw house is not far from where the body was found. The police found suspicious blood on the doorframe, brick pier, pillow and white shirt of Lu Tianhui’s residence. During the search, the police also found several obscene books and diaries with women’s names on them. Later, all these became evidence and appeared in several judgments in this case.

  Lu Tianhui told The Paper that he left home and lived alone because he and his mother were unhappy about family affairs, and at that time he often sifted sand on the river Bao during the day before moving to the thatched cottage. On the night of the murder, he went to the village accountant’s home to issue a remittance certificate. When he returned to the hut, it was past nine o’clock. After reading for a while, he fell asleep. He said that the white shirt found by the police was an old one he didn’t wear. It had not been washed for several months, and it was usually used to cover the quilt to prevent dust.

  The blood test certificate issued by HanzhONg Public Security Bureau on October 6, 1994 shows that the blood on the door frame and Lu Tianhui’s white shirt is ON type, which is the same as Lu Li’s hair and bone blood type, while Lu Tianhui’s blood type is AMN type.

  On October 15th of the same year, the police formally detained Lu Tianhui. The only notice of arrest on file shows that Lu Tianhui was taken away by the police for questioning on September 16, and in the following 30 days, the Hantai Branch made a total of nine transcripts. Deng Xueping believes that this does not comply with the provisions of the Criminal Procedure Law that "the maximum duration of summons and detention shall not exceed 12 hours".

  According to the investigation report, Lu Tianhui confessed the whole process of raping and killing Lu Li under the strong offensive of "repeated policy education" and "putting facts and reasoning" by the police. On October 22, Lu Tianhui was arrested by Hanzhong Public Security Hantai Branch for intentional homicide and rape.

  After the court returned the investigation for four times, the defendant was sentenced to life.

  In December 1994, Hanzhong City Procuratorate sued the case to Hanzhong Intermediate People’s Court, and in the following five years, Hanzhong Intermediate People’s Court returned the case for supplementary investigation four times.

  According to the four return letters in the case file, the court asked for supplementary investigation on the cause of Lu Li’s death, how the blood on the white shirt was formed, the process of blood extraction, whether there was a confession by torture, the possibility of excluding others from committing crimes and the evidence to confirm the facts of adultery. On November 24, 1998, Hanzhong Intermediate People’s Court made a decision to withdraw the investigation for the fourth time, saying that "after repeated withdrawals, the facts of this case were unclear and the evidence was insufficient", and there were many doubts and there was no statutory case. In this regard, the police issued a number of "Notes".

  On September 21, 1995, when the first trial of the case was held, Lu Tianhui retracted his confession in court, claiming that the guilty confession was made at the instigation of the case-handling personnel. After Lu Tianhui was detained for more than four years, on May 21, 1999, Hanzhong Intermediate People’s Court sentenced Lu Tianhui to life imprisonment for intentional homicide, 15 years imprisonment for adultery with a young girl, combined punishment for both crimes, and combined execution of life imprisonment.

  The judgment found that at 8: 00 pm on August 8, 1994, Lu Tianhui rode back to her residence and went to Doumen, Gaoyan. When she met Lu Li walking independently, she tricked her into a depression outside an old pumping station in Quluying Village Forest Farm and raped her. For fear of being exposed, Lu Tianhui covered Lu Li’s mouth with his left hand, pinched her neck with his right hand, kneeled her abdomen with her knees, and slammed a cement block on her forehead to death. After the murder, Lu Tianhui wrapped the body in a plastic woven bag, moved it to the rice field 150 meters away, pulled out some rice by hand, dug the pit by hand and buried the body, and then replanted the pulled rice.

  The Paper noted that in the list of physical evidence shown in the judgment, the cement block of the murder weapon and the woven bag of the corpse removal tool were not included. According to the file data, the police handling the case gave an explanation in October of the year of the incident, saying that the investigator "has not found it after more than two hours of serious search", and this handwritten case description was not stamped with the official seal.

  In addition to the confession, the most important evidence of the verdict is blood group identification. Deng Xueping, Lu Tianhui’s complaint agent, pointed out that according to the case file, the case-handling unit never extracted DNA from the bones, nor did it conduct DNA identification. Under this circumstance, it was impossible to confirm that the blood on Lu Tianhui’s white shirt and door frame came from Lu Li. "Blood type identification is not exclusive, and there is no direct evidence to prove that Lu Tianhui killed people."

  The Paper noted that the article "DNA identification technology and its application in criminal investigation" in the fourth issue of "China Judicial Appraisal" in 2007 recorded that since 1993, DNA identification technology has been widely used in criminal investigation in China.

  In June 1999, Lu Tianhui appealed because he refused to accept the judgment of the first instance. Three months later, the Shaanxi High Court made a final ruling, rejected his appeal application and upheld the original judgment.

  The Paper noted that in the defense opinions of the defenders of the first instance recorded in the judgment, it was mentioned that "the court was advised to impose appropriate punishment" on the grounds that Lu Tianhui was guilty of adultery and murder of a young girl, which was based on indirect evidence such as on-site inspection and criminal scientific and technical appraisal. Hanzhong Intermediate People’s Court held that "the defense opinions of defenders can be adopted."

  Deng Xueping believes that in the case that Lu Tianhui refused to plead guilty and repent and did not make any financial compensation, the sentence of combined punishment for two crimes was indefinite, "there is room for it."

  There is a big difference in the comparison data of footprints. The police said that they could not find similar conditions.

  The Paper noted that out of the nine transcripts made by Lu Tianhui to the police, there were two confessions of innocence and seven confessions of guilt. The first guilty confession was made on September 26, the tenth day after Lu Tianhui was arrested, and just one day later, Lu Tianhui made another innocent confession. In its seven guilty confessions, there are inconsistencies in the victim’s dress, his own dress, tools for committing crimes, the killing process, and the time of taking the tools for throwing the body.

  Lu Tianhui told The Paper that during the interrogation, he was tortured to extract a confession. Today, he still has two crimson scars on his calves.

  In the first instance of this case, Hanzhong Intermediate People’s Court also investigated whether there was a confession by torture, and Hantai Branch and investigators issued two written certificates to deny it.

  When Hanzhong Intermediate People’s Court sent the case back to the procuratorate for supplementary investigation for the fourth time, it asked Hantai Public Security Bureau to explain whether to compare the data of "Chengtangjiaowo" extracted during the investigation with that of Lu Tianhui. Hantai Branch issued a "Description" to the court five years after the case was detected, saying that "because the time, space and place that coincided with the original scene could not be found at that time, the measurement data were quite different".

  According to the "Description", the foot fossa found during the on-site investigation of the bones was 6 cm deep and 23 cm long, and the stride was 87 cm, while Lu Tianhui’s foot was 23.5 cm long. He was carrying stones equal to Lu Li’s weight, and the stride obtained after simulating barefoot natural walking twice in the sediment field near the original site was far less than 87 cm, namely: the first step: the left stride was 77 cm, 77 cm, 78 cm, and the right stride was 79. The second pass: the left step is 60 cm, 57 cm and 61 cm, and the right step is 65 cm, 61 cm and 63 cm.

  Deng Xueping therefore believes that the public security organs did not transfer the data that might prove Lu Tianhui’s innocence or light crime to the procuratorate for the first time.

  After being released from prison, he appealed and the Shaanxi High Court filed a case for review.

  In June 2004, due to Lu Tianhui’s persistent complaint, Hanzhong Intermediate People’s Court filed a case for review. According to the case file, when the organizer revisited the site on July 26 of that year, he personally went to the field to test and simulate the details of "pulling rice by hand". However, the conclusion was that after a night of heavy rain, the soil in the field was still hard, and the two feet stood on the mud, and they could only step down to the arch of the foot, or they could only step down to the outer edge of the back of the foot. Because the rice grew to a late stage and the roots were deep, the organizer could not pull rice by hand at all.

  Five months after the investigation, Hanzhong Intermediate People’s Court decided to reject the appeal. According to the case file, Yajun Gao, then the director of Sujiaying Police Station, said in a telephone inquiry during the reexamination of Hanzhong Intermediate People’s Court that the important evidence of Lu Tianhui’s case was blood, "blood proved that he killed the little girl".

  On October 18th this year, The Paper tried to contact Yajun Gao by telephone, but got no response.

  In January this year, after three commutes, after being detained for more than 24 years, Lu Tianhui was released from prison. He returned to his hometown to live with his mother and still insisted on appealing for himself.

  Lu Tianhui told The Paper that his father died young. As the eldest son of his family, he went home to farm after graduating from high school. At that time, his relatives used to act as matchmakers for him, but he couldn’t make it because of financial difficulties.

  On October 16th, The Paper learned from Shaanxi Higher People’s Court that the court had initiated a case review of Lu Tianhui’s case, and the relevant staff said that it was not convenient to disclose the latest progress of the review. (Reporter Wei Jiaming)

Pre-cooked vegetables are rushing, and self-heating food "rice bowl" is hard to protect?

"The prefabricated vegetable market is hot, and everyone is cooking prefabricated vegetables now. In the future, the rice bowl of self-heating food may be lost!"

Recently, at a food exhibition, the operator of a food enterprise sent such feelings to the insight of prefabricated dishes. Is this really the case? Do prefabricated dishes really stand in the way of self-heating food?

The potential energy of self-heated food has declined, but the prepared food has been rising all the way.

Before exploring the above problems, it is necessary to look at the definition of self-heating food and prepared vegetables.

According to the Classification of National Economic Industries, foods made from rice, wheat flour, miscellaneous grains, etc., which can be used as staple food only by simple cooking, are called convenience foods.

Thus, both self-heating food and prepared vegetables belong to convenience food.

Because self-heating food also belongs to pre-packaged finished or semi-finished food, there are also views that self-heating food is a kind of prepared food.

However, in the eyes of most food producers and operators, self-heating food is a rice or vegetable package made of modern technology that can be stored for a long time. It can be eaten by heating with its own heating package, which is highly standardized and can achieve long-term preservation and longer transportation distance.

However, for some dishes with complicated cooking procedures, prefabricated dishes are convenient dishes formed by using modern standardized flow process to prepare the raw materials in the early stage, simplify the production steps, pack them in a hygienic and scientific way, and then heat or steam fry them.

It can be seen that self-heating food is more convenient than prefabricated dishes, and it can be completed without going through the kitchen and cooking, but prefabricated dishes often need to be cooked simply.

In fact, self-heating hot pot probably rose at the end of 2015, and broke out in the e-commerce platform in 2017. According to public data, on the day of Tmall double 11 in 2017, self-heating hot pot products sold 1.7 million copies; In 2018, the popularity of self-heating hot pot increased explosively, and double 11 sold 4.53 million copies of self-heating hot pot that day, up 1.7 times year-on-year.

The hot market has spawned brands that focus on the field of self-heating hot pot, such as self-cooking pot and Mo Xiaoxian. At the same time, it also attracted enterprises from Haidilao, Dezhuang, Uni-President, Jinmailang, Master Kong, Baixiang, Zhengda, Liangpin Shop and so on.

Therefore, self-heating hot pot was once the same, and even considered as a substitute for instant noodles. However, since the second half of 2020, the heat of self-heating food has begun to fade. With the influx of a large number of brands, while expanding the market, there have been a lot of low-price competition, homogeneous competition and even some safety accidents in the self-heating food market, which have had a bad impact on the whole industry.

An enterprise manager who provides heating packages for self-heating food factories once told Xinhua that since the second half of 2020, the heat of self-heating food has declined, and the orders for heating packages have dropped significantly. In the face of market changes, the factory has to adjust the product structure to avoid being more affected.

"A wave of people buy self-heating food for early adopters. After curiosity, the overall sales volume will inevitably decline." The person in charge of a self-heating food brand said.

The evaluation and notes of many consumers on social platforms also show that in recent years, everyone’s enthusiasm for self-heating food is gradually fading.

However, while the potential energy of self-heated food has declined, the prepared food has started to rise all the way.

According to statistics from Deloitte, the market size of China’s pre-cooked vegetables is about 550 billion yuan in 2021, and the compound growth rate in the next five years is expected to reach 13%, and the market size is expected to reach 1 trillion by 2026.

"It also meets consumers’ demand for convenient and fast food, and can also bring consumers multiple experiences of cooking and enjoying food at home. The fiery heat of prefabricated dishes will inevitably affect self-heating food." Some food producers and operators stressed this.

What’s more, it is believed that in the future, pre-cooked dishes will divide the market of self-heating food and gradually replace self-heating food.

Will prefabricated dishes take away the "rice bowl" of self-heating food?

Pre-cooked food insight believes that pre-cooked food and self-heating food are not competitive.

First of all, the target consumers of pre-cooked vegetables and self-heating foods are not completely coincident. According to the data of Tmall, 47.75% of the consumers of self-heating hot pot are 18-24 years old, 19.61% are 25-29 years old, and nearly 50% are college students and white-collar workers who have just entered the workplace. Self-heating hot pot is more suitable for lazy economy and fast-paced life because it can be eaten anytime and anywhere without fire or plug-in.

The main consumer groups of prefabricated dishes (here only refers to C-end consumer groups) are those who can cook, pay attention to health, have high requirements for food safety, have relatively high quality of life and are relatively insensitive to prices. Among them, the majority are urban people who have families and children and pay more attention to health and quality of life.

Secondly, the application scenarios of the two types of products are also very different. To a certain extent, both prepared dishes and self-heating foods are convenient and quick solutions for people to have a meal. However, consumers choose to eat self-heating food, mostly in the scenes of eating alone, working overtime and staying up late, and traveling; However, prefabricated dishes are more common in family meals, dinners and other scenes. Therefore, compared with self-heating food, consumers will have higher expectations for prefabricated dishes, and the demand for "eating well" will be more obvious.

It can also be seen from the market sales of prefabricated vegetables. Data from JD.COM, Tmall and other platforms show that most of the pre-cooked dishes with high sales volume are common "hard dishes" on the dining table, such as braised pork with plum vegetables, pork belly chicken, fish with pickled vegetables, Buddha jumping over the wall and so on. Some insiders commented that the consumption of prefabricated vegetables reflects consumers’ pursuit of consumption upgrading and quality life on the basis of convenient life.

It can be seen that the pre-cooked food and self-heating food face different groups of people, and the demand they can meet is slightly different. They are not absolutely competitive, and it is basically impossible for pre-cooked food to completely replace self-heating food.

The key to the future development of prefabricated dishes is quality, richness and high cost performance.

Considering that the product attributes of prepared food and self-heating food are very close, the shackles encountered in the development of self-heating food are also worth thinking about and learning from. For example, the homogenization is serious, the quality is not guaranteed, and the cost performance is low.

"I bought a prefabricated Buddha jumping wall, which is not delicious and the price is not affordable. It is better to order takeout with this money! "

"It seems that there are only a few kinds of prefabricated dishes. Take pickled fish as an example. The tastes of products from different brands are not too different. If you eat more than a few times, you will get bored and you will no longer be interested. "

"Eating is the taste of industrial additives. Where is it delicious?"

……

On social platforms, it is not uncommon for consumers to comment on prefabricated dishes and the like.

How to improve the user’s eating experience? Prefabricated dishes insight has communicated with many people in the industry. It is generally believed that in order to break through the dilemma of self-heating food in the future, prefabricated dishes need to make great efforts in three aspects: product quality, dish type and product cost performance.

In terms of product quality, it is necessary to ensure the safety of ingredients and improve the taste of products. In order to meet consumers’ demand for "eating well", prefabricated dishes should be oriented towards "delicious, nutritious and healthy".

In terms of the types of dishes, the brand of prefabricated dishes can not only increase the SKU of products, but also develop more differentiated niche ingredients and special dishes according to the diversified needs of consumers, such as Anjing Food’s introduction of new prefabricated dishes of soft-shelled turtle and puffer fish in the world of Chinese fish, etc. There is still a lot of room for exploration in the variety of prefabricated dishes.

In terms of product price, under the trend of more and more obvious consumption degradation, the ultimate cost performance is also an important measure for consumers to choose products. In terms of price, if the price of prepared dishes is basically the same as that of take-away, or even higher than the take-away price, it will be difficult to attract consumers.

After the epidemic, the social economy is constantly recovering, consumers’ confidence in future income growth is still insufficient, and the wave of consumption degradation in the catering industry will continue.

Under such circumstances, imagine how many people would refuse a delicious, easy-to-cook and inexpensive prepared dish.

(Contributed by: Red Meal Industry Research Institute)