Recently, the FDA released the annual report on new drugs in 2022. The data shows that the FDA approved 37 innovative drugs to be listed last year, with the number reaching a new low of nearly six years, of which nearly 50% have been listed in China or are in the review stage. The FDA promotes and speeds up the evaluation of new drugs in various ways through "multi-pronged approach". In 2022, a number of domestic innovative drugs "went out to sea" to break through the FDA, and the results were "mixed". Two domestic innovative drugs were approved by the FDA and four hit a wall.

Figure 1: Number of new drugs approved by FDA in recent ten years

Source: FDA2022 Annual Report on New Drugs (New Drug Therapy Approvals 2022).

37 innovative drugs were approved, and 18 accelerated the entry into the China market.

Recently, the Center for Drug Evaluation and Research (CDER) of FDA released the annual report of new drugs in 2022. In 2022, the FDA approved the listing of 37 innovative drugs, with the number reaching a new low of nearly six years. Among the approved innovative drugs, 20 (54%) belong to "first-in-class" innovative drugs, and 20 (54%) are drugs for rare diseases.

As the benchmark of global pharmaceutical supervision, FDA has approved 28 new drugs (76%) in the first round, and 25 (68%) in the United States before other countries.

In 2022, FDA promoted and accelerated the evaluation of new drugs in various ways through "multi-pronged approach". Twelve (32%) were identified as fast-track, 13 (35%) were identified as breakthrough therapeutic drugs, 21 (57%) were identified as priority review, and 6 (16%) were accelerated for approval. CDER used one or more accelerated development and review methods for 24 (65%) of all new drugs approved in 2022.

Table 1: Innovative Drugs Approved by FDA in 2022

Source: FDA website, intranet database.

In recent years, more and more attention has been paid to innovative drugs in China. In 2022, innovative drugs approved in the United States are also running into the China market at "China speed" to solve the unmet health needs of more China patients. According to statistics, at present, 18 (49%) innovative drugs are at the stage of clinical application and above in China. Among them, four innovative drugs, namely, abcixinib, voronoxan, benvimod and pessolizumab, have been approved for marketing, while otconazole and deuterium colexitinib are in the application stage, while nine innovative drugs are in clinical phase III, one in clinical phase I and two in clinical application.

Table 2: Research and Development of Innovative Drugs in China

Source: Minenet database

Two domestic innovative drugs "went to sea" successfully, and legendary creatures actively expanded their territory.

In 2022, a number of domestic innovative drugs "went out to sea" broke through the FDA, and Sidakio Orense and Benvimod returned gratifying news and were successfully approved for listing.

On February 28th, 2022, the BCMA CAR-T drug Cedactylosin developed by Kingsley’s Legendary Biology was approved by FDA for the treatment of relapsed or refractory multiple myeloma. Cedactylosin became the first cell therapy product approved by FDA in China and the second CAR-T cell immunotherapy approved for BCMA in the world. This is a beautiful "turnaround" after the FDA announced the tightening of China’s listing policy for innovative drugs, which means that China has officially entered the world’s first-line position in the field of cell therapy.

After the successful listing in the United States, Sida Chiolense also extended its listing territory to the European Union and Japan in 2022. In May, 2022, the European Commission (EC) has granted conditional marketing permission to Cedactylosin for the treatment of adult patients with relapsed or refractory multiple myeloma who have received at least three treatments in the past, including immunomodulatory drugs, proteasome inhibitors and anti-CD38 antibodies, and the last treatment showed disease progression. In September, 2022, the Japanese Ministry of Health, Labor and Welfare approved Cedactylosin for the treatment of adult patients with recurrent or refractory multiple myeloma. At present, in China, Sida Chiolense is in the stage of applying for listing.

Figure 2: Global R&D progress of Sida Chiolense.

On May 24th, 2022, Dermavant Sciences announced that the FDA had approved the marketing of VTAMA (Benvimod, 1%) cream for the local treatment of adult plaque psoriasis. Benvimod, developed by Tianji Medicine, a domestic enterprise, is the first-in-class new drug with independent intellectual property rights.

In 2012, GSK obtained the overseas development right of Benvimod with a down payment of nearly $200 million. In July 2018, GSK announced that it would sell the overseas development right of Benvimod to Dermavant for $330 million.

As early as May 2019, Benvimod was approved to be listed in China as a "Class 1 new drug" for adults with mild to moderate stability psoriasis vulgaris suitable for local treatment. So far, benvimod is the first innovative drug approved by the FDA after it was approved for marketing in China.

Figure 3: Global listing of Benvimod

The road to "going out to sea" is not smooth. Cinda Bio and Junshi Bio … find another way out.

The road to "going out to sea" was not smooth sailing. In 2022, the innovative drugs of Cinda Bio, Junshi Bio, Hutchison Whampoa and Baekje Shenzhou all submitted their applications for listing in the FDA, but they were rejected by the FDA one after another.

Table 3: Drugs not approved by FDA in 2022

In March, 2022, Cinda Bio announced that FDA refused to approve the listing application of new drugs for the first-line treatment of patients with non-squamous non-small cell lung cancer, including cindilizumab combined with pemetrexed and platinum chemotherapy. In its reply to Cinda Bio, FDA pointed out that the related product trials of Cinda Bio were only conducted in China, not global multi-center clinical trials, and the results were not applicable to patients in the United States due to the nature of a single country.

In May, 2022, Hutchison announced that the US FDA had not approved the application of Suo Fan tinib for the marketing of new drugs for the treatment of pancreatic and non-pancreatic neuroendocrine tumors. The reason for FDA’s rejection of Hutchison is similar to Cinda Bio’s. It thinks that the data package of Hutchison based on two successful China Phase III studies and an American bridging study is not enough to support the drug’s approval in the United States, and more international multi-center clinical trials representing American patients need to be included to support the approval in the United States.

In the same month, Junshi Bio’s application for the marketing of PD-1 antibody Treprilizumab received a complete reply from FDA, requesting a quality control process change. This process change was rejected because the facilities could not be inspected on site due to travel restrictions during COVID-19.

In July, 2022, Baekje Shenzhou announced that the FDA of the United States could not complete the required on-site verification work in China as scheduled due to travel restrictions related to the COVID-19 epidemic, so it would extend the completion time of the target review of the application for the new drug listing license for second-line esophageal squamous cell carcinoma. However, its partner Novartis revealed in the quarterly report that it had cancelled the listing application for the treatment of non-small cell lung cancer with tierellizumab in the United States.

In the face of the "ruthless" rejection of the FDA, Junshi Bio quickly made adjustment measures and resubmitted the application for the listing of Trepril monoclonal antibody to the US FDA. The FDA has set the date of PDUFA as December 23rd, 2022. Trepril monoclonal antibody is still in the approval stage, and there is no clear result. Hutchison Whampoa said that it is working with the FDA to evaluate the next step. Baekje Shenzhou is rumored to move to Europe, and it is expected that it will submit its first listing application in the EU in 2023. Cinda Bio announced at the end of the year that it had recovered the overseas rights and interests of Cindilizumab from its partner Lilly Pharmaceutical.

There are many cases of domestic innovative drugs failing to go to sea. On the one hand, FDA has high requirements for domestic pharmaceutical companies’ products going to sea. According to the FDA’s previous requirements for Cinda Bio, if the new PD-1 wants to be listed in the United States, it needs to compete with the existing standard therapies. And drug K has been approved for dozens of indications in the United States, and products with the same indications have to cross the mountain of drug K if they want to be approved. On the other hand, at present, how to conduct clinical trials of domestic innovative drugs overseas is still in the exploratory stage. These failed cases essentially reflect the doubts of foreign mature markets on the quality of clinical trials in China.

tag

2022 has passed, and the innovative drugs approved by FDA are the direction of global innovative drug research and development trends, leading the way for innovative pharmaceutical companies. For domestic innovative pharmaceutical companies, if they want their products to go abroad, there is no doubt that they should sum up their previous experience in innovating drugs in the FDA, always pay attention to the changes in the clinical pattern, and keep in touch with the FDA for clinical design. At the same time, we should improve our products from many dimensions, such as reflecting the innovation of products, meeting unmet clinical needs, improving drug accessibility, improving technology, selecting indications, and improving safety and efficacy.

Source: Minenet comprehensive database.

This article is an original manuscript, please indicate the source and author, otherwise the tort liability will be investigated.

　　Xinhua News Agency, Beijing, December 1st (Reporter Pan Yi, Wang Yao, Wei Hua) A highly anticipated delegation of mainland Olympic athletes will arrive in Hong Kong on December 3rd for a three-day exchange activity. A total of 29 athletes from track and field, swimming, diving, weightlifting, gymnastics, trampoline, rowing, kayaking, cycling, fencing, table tennis and badminton participated in the Tokyo Olympic Games. The following are biographies (in order of projects):

　　"Asian Flying Man": Su Bingtian

　　In the men’s 100-meter semi-final of the Tokyo Olympic Games, Su Bingtian broke the Asian record at a speed of 9.83 seconds, ranking first in the semi-final and advancing to the final, becoming the first Chinese to stand on the runway of the Olympic men’s "flying man" final. After that, Su Bingtian won the sixth place in the final in 9.98 seconds, setting a new record. Running for 10 seconds twice in such a short time is a miracle in Asia.

　　Women’s shot put champion: Gong Lixiao.

　　Gong Lixiao has been practicing shot put for 21 years, and she is the leader of women’s shot put in China. At the Tokyo Olympic Games, Gong Lixiao, as the "four-dynasty veteran" of the Olympic Games, wrote the "Veteran Legend". In the final, she refreshed her personal best again and again, and finally won the championship with 20 meters 58. This is also the first gold medal in field events in the history of China Olympic Games.

　　Women Javelin Champion: Liu Shiying

　　At the Tokyo Olympic Games, Liu Shiying won the women’s javelin gold medal with a score of 66.34 meters, becoming the first person in China and even Asia to win the Olympic javelin gold medal. At the critical moment, strength plus a stable mentality played a decisive role.

　　Women’s 4X200 freestyle relay champions: Yang Junxuan and Tang Muhan.

　　In the women’s 4X200 freestyle relay final of Tokyo Olympic Games, Yang Junxuan and Tang Muhan cooperated with Zhang Yufei and Li Bingjie to win the championship and break the world record with 7 minutes 40.33 seconds.

　　Yang Junxuan swam first, giving China a lead. Tang Muhan, the second best player, extended China’s lead from 0.14 seconds when he received the bat to 0.45 seconds when he handed it over.

　　Yang Junxuan is quiet and likes painting and calligraphy. She is a "talented girl" in the swimming team. On holidays, the gifts she often gives are hand-painted paintings, couplets and blessings.

　　Diving Men’s Double Single 3m Slab Double Champion: Xie Sicai

　　At the Tokyo Olympic Games, Xie Sicai won the men’s 3m springboard synchronized gold medal with Wang Zongyuan, and then defeated Wang Zongyuan to win the men’s 3m springboard gold medal. Wang Zongyuan won the silver medal. Xie Sicai also became the second athlete to win the men’s 3m springboard "double champion" in a single Olympic Games after Xiong Ni, the diving prince.

　　Xie Sizhen suffered a serious ankle fracture in 2014, and two steel nails and a rivet were implanted in the injury. The doctor warned him that he could no longer practice diving. However, he refused to surrender to fate.

　　Diving men’s synchronized 3m springboard champion: Wang Zongyuan.

　　In Tokyo, Wang Zongyuan, who played in the Olympic Games for the first time, won the gold medal in the men’s synchronized 3m springboard with Xie Sichai, which was the only event that China’s diving "dream team" missed in Rio Olympic Games. Wang Zongyuan and Xie Sichai succeeded in making up for this regret.

　　Women’s 49 kg weightlifting champion: Hou Zhihui

　　Hou Zhihui won the gold medal with a total score of 210kg in the women’s 49kg weightlifting competition in Tokyo Olympic Games. The coach’s evaluation of her is "high concentration and good coordination, and she is an athlete who trains with her brain".

　　Women’s weightlifting 87kg champion: Wang Zhouyu

　　The women’s 87 kg class is a new level set by the International Federation of Weightlifting in 2018. Wang Zhouyu rose from the 76 kg class. It is not everyone’s wish to gain 10 kg.

　　Women’s weightlifting champion over 87kg: Li Wenwen.

　　Li Wenwen is cheerful, and once became popular on the Internet because of a small video of sleeping on the floor. She once joked: "Every fat girl has her own dream."

　　Weightlifting men’s 61kg champion: Li Fabin

　　In the national team with many experts, Li Fabin didn’t get the chance to participate in the Olympic Games until he was nearly 30 years old. In the final in Tokyo, Li Fabin’s "Golden Rooster Independence" shocked the world.

　　Men’s 67 kg weightlifting champion: Chen Lijun

　　In the final of the Tokyo Olympic Games, due to the poor performance of snatch, the Huli Army was 11 kilograms behind its Colombian opponent. However, he only used one of the last two clean and jerk opportunities to reverse the turnaround and successfully lifted 187 kilograms, an astonishing 12 kilograms more than his last attempt.

　　Men’s 73kg weightlifting champion: Shi Zhiyong.

　　Won the men’s weightlifting 73kg class in Tokyo Olympic Games and broke the world record in total score. At the age of 11, Shi Zhiyong went to Ningbo alone with a woven bag, and later became the 69kg champion of the Rio Olympic Games. After the Rio Olympic Games, the International Weightlifting Federation adjusted the weightlifting level, and he was upgraded to 73kg, but it didn’t beat Shi Zhiyong. Since 2018, he has continuously set a world record, and he stands out in the 73 kg class.

　　Men’s weightlifting 81kg champion: Lv Xiaojun.

　　Lv Xiaojun is the weightlifter who won the most Olympic medals in China and became the oldest Olympic champion in weightlifting history at the age of 37. This is also his second Olympic gold medal in his life after winning the gold medal at the London Olympics.

　　The champion of men’s gymnastics parallel bars: Zou Jingyuan

　　Zou Jingyuan’s parallel bars strength can be described as a ride in the current men’s gymnastics world. In the parallel bars final of the Tokyo Olympic Games, his almost perfect movements left no chance for his opponents to surpass him.

　　Men’s Gymnastics Rings Champion: Liu Yang.

　　Liu Yang’s rings are as beautiful as a textbook. At the Tokyo Olympic Games, his "Wang Zhi’s contempt" for turning his neck on the rings was described by the official Twitter of the International Olympic Committee as: "How can someone look so cool while competing on the rings!"

　　Women trampoline champion: Zhu Xueying

　　On August 28th, 2021, Zhu Xueying donated her Olympic gold medal and award-winning clothing to Tianjin Sports Museum, becoming the first athlete to donate the gold medal of Tokyo Olympic Games. She said, "It is more meaningful to display the Olympic gold medals in the museum than at home. I look forward to more audiences entering the exhibition hall, feeling the Olympic spirit, feeling the charm of sports culture and drawing on the strength of forging ahead. "

　　Women’s rowing quadruple sculls champions: Cui Xiaotong, Lu Yang, Zhang Ling and Chen Yunxia.

　　Cui Xiaotong, Zhang Ling, Chen Yunxia and Lu Yang worked closely together to lead the way in the women’s rowing quadruple sculls final of Tokyo Olympic Games, winning the championship with the world’s best result of 6: 05.13.

　　Cui Xiaotong, who has an excellent sense of water, as the No.4 rower, has well controlled the rowing rhythm of the four people. Cui Xiaotong, who used to practice single oar, only changed to practice double oars three years ago, but she trained hard and made rapid progress. She often said, "If you don’t torture yourself in training, you will be tortured by your opponent in the game."

　　As the No.2 rower, Zhang Ling is the driving force of the whole boat. As the No.1 rower with the highest technical requirements, Chen Yunxia kept the balance of the whole boat well. She changed to rowing after practicing track and field for five years, and her physical fitness is outstanding. Lu Yang, the No.3 rower, plays the role of all-round assistant, on the one hand, helping the No.4 rower to control the rhythm, on the other hand, helping the No.2 rower to become the strength support in the rowing process.

　　Still water women’s 500m synchronized rowing champion: Xu Shixiao and Sun Mengya.

　　In the final of the still water women’s double rowing in Tokyo Olympic Games, Xu Shixiao and Sun Mengya teamed up to win the championship with the best performance in the Olympic Games, winning the first Olympic gold medal for the China women’s canoeing team in history.

　　Xu Shixiao, who became famous at a young age, has experienced injuries, retirement and comeback. Xu Shixiao said that kayaking is a kind of feeling for her. Although there are losses and valleys in the process, these eventually become the driving force on her way forward.

　　Sun Mengya, who entered the sports school only one year ago, almost gave up kayaking because of her father’s injury, but she finally persisted.

　　Champion of track cycling women’s team racing: Zhong Angel

　　At the Rio Olympic Games five years ago, Zhong Angel partnered with gong jinjie to win the gold medal in this event, achieving the breakthrough of "zero" in China’s cycling Olympic gold medal. At the Tokyo Olympic Games, Angel Zhong and Bao Shanju broke the world record of women’s team racing held by China in 31.804 seconds, and defeated the German team in the final, winning the second cycling gold medal for China in Olympic history.

　　Women’s individual epee champion: Sun Yiwen

　　At the Tokyo Olympic Games, Sun Yiwen won the first women’s weightlifting individual gold medal in the history of China Olympic Games in the final overtime, becoming the first China fencer to win individual medals in two consecutive Olympic Games.

　　Table tennis men’s singles and men’s team champion: Malone

　　Malone is the first winner of men’s double slam and full slam in the history of world table tennis. Tokyo Olympic Games has become a stage for Malone to constantly refresh history. Beating the world number one Fan Zhendong to win the gold medal in men’s singles, Malone became the first defending man in the history of Olympic table tennis and the player with the most world titles in the history of table tennis.

　　Table tennis men’s team champion: Xu Xin.

　　Left-handed straight, unique play. In October this year, at the Asian Table Tennis Federation Congress held in Doha, Qatar, Xu Xin was elected as the vice chairman of the Asian Table Tennis Federation.

　　Badminton mixed doubles champions: Wang Yilu and Huang Dongping

　　In the badminton mixed doubles final of Tokyo Olympic Games, Wang Yiliu’s partner Huang Dongping, who participated in the Olympic Games for the first time, defeated teammate and top seed Zheng Siwei/Huang Yaqiong 2-1.

　　Wang Yilu has outstanding physical fitness and firm will. He often says: "What people fear most is that they have no goal, just like salted fish. With clear goals, happiness will increase. "

　　Huang Dongping often reminds himself: "No matter whether there is harvest or not, it is definitely right to pay."

　　Review of "Looking Back on the Extraordinary Five Years" Series;

　　Song Yan

　　In the past, the barren land was covered with "green clothes", and the black and odorous water body was "transformed" into an ecological river, and remarkable progress was made in the control of atmospheric smog … … A beautiful picture of China with green hills, flowing green water and fresh air is slowly spreading out on this 9.6 million square kilometers land.

　　A good ecological environment is the most inclusive welfare of people’s livelihood. Since the "Thirteenth Five-Year Plan", with the goal of "overall improvement of ecological environment quality", China has adhered to green development, continued to "overweight" environmental governance, resolutely fought the tough battle of pollution prevention and control, increased the protection of ecosystems, and significantly improved the ecological environment, handing over a heavy green "report card".

　　In the past five years, the system of ecological civilization system has become more perfect. The construction of ecological civilization needs institutional escort. In the past five years, major breakthroughs have been made in the reform of the ecological civilization system; The pace of environmental rule of law is accelerating, and environmental protection law is more deterrent and executive; The "green storm" set off by the central environmental protection inspector swept across the country, realizing the transformation of ecological environmental protection from "inspecting enterprises" to "supervising government"; The long river and lake system has injected new vitality into China’s water pollution control … … It is gradually becoming a consensus to use institutional civilization to protect ecological civilization.

　　In the past five years, the concept of green development has been deeply rooted in the hearts of the people. In the past, digging mountains to "sell stone mines", but now protecting green and "building a golden nest"; Shut down "small scattered" and exert "high precision"; The pace of energy structure adjustment is accelerated, and the development is moving towards cleanliness … … Five years have passed quickly, and the development concept of "Lucid waters and lush mountains are invaluable assets" has been deeply rooted in the hearts of hundreds of millions of people and has become the consensus and common sense of the whole society. From the Yellow River to the Yangtze River, from Babusha Forest Farm to Kubuqi Desert, the green legends written in rivers, lakes and the Gobi Desert are vivid interpretations and powerful proofs.

　　In the past five years, the ecological dividend has been continuously released. Environment is people’s livelihood, green hills are beautiful, and blue sky is also happiness. In the past five years, China’s green "territory" has been continuously expanded, the ecological environment has been significantly improved, the green development dividend has been continuously released, and the people’s sense of ecological environment acquisition, happiness and security have been continuously enhanced. The lush forests and bamboo seas have become "green banks" for villagers to get rid of poverty and become rich, and more and more villages rely on beautiful scenery to eat "tourist meals". The data shows that by the end of May 2020, through the implementation of ecological poverty alleviation, more than 3 million poor people across the country have been lifted out of poverty and increased their income.

　　In the past five years, the "China Program" for ecological civilization construction has benefited the world. China’s fungus and grass technology with completely independent intellectual property rights has spread to more than 100 countries and regions; China science and technology help Central Asian countries "turn green"; Experts from many countries in the Middle East came to China to study the sand fixation method of building oases in the desert … … More and more China’s ecological management experience has gone abroad and spread to more countries and regions, contributing wisdom and strength to building a better earth home.

　　People live up to the castle peak, and the castle peak lives up to people. The construction of ecological civilization is closely related to everyone, and everyone should be a practitioner and promoter. Let’s start with less plastic bags and more green trips, start with small things and start around us. Let’s join hands to add green to the earth, make the sky blue, land green and water clean become the norm, draw a beautiful picture of harmonious coexistence between man and nature, and relay to protect our green home in the next five years.

　　Yesterday (17th), Voice of China reported that a dangerous building in qiongshan district, Haikou City, Hainan Province was required to be demolished. As a result, not only was it not demolished, but it also became a regular commercial house. Now this building has been identified as a D-class dangerous building. The building is seriously tilted, and a bottle of mineral water on the ground in the room can roll. However, some residents still live in dangerous buildings because they are not properly resettled, and their lives are threatened. (previously reported) 　

　　After the report was broadcast, Haikou and qiongshan district responded immediately.On the morning of the same day, people were sent to resettle residents from dangerous buildings, and the suspected violations of laws and regulations during the relevant procedures were thoroughly investigated, and the responsibilities would be seriously investigated.

The latest response from the local street office: residents can live in resettlement houses.

Or subsidize 1000 yuan to rent his own house every month.

　　Building 27, Qingzhu Street, qiongshan district, Haikou City, was built in 1993. At that time, it was approved to build three floors, but it was built to eight floors. In 2003, due to the serious inclination of the house, it was designated as a dangerous building by the former Planning and Construction Bureau of qiongshan district, and it was required to be demolished.

△ The dangerous building is seriously tilted, and the mineral water will roll.

　　In 2007, this dangerous building, which had to be demolished, went through the formalities of commercial housing, and then went on the market. Until July 2022, this building was identified as a dangerous building again, and all residents were required to move out. However, after the residents were settled in the hotel for three months, no one took care of them, and some residents moved back to dangerous buildings to continue living.

　　On the morning of the Voice of China report, many functional departments of qiongshan district came to the building downstairs.Resettlement of residents who are still living. 　 　

　　Street office staff:They are moving out today. Let them out first. There are dangers in this house.

△ After the report was broadcast, the staff came to work under the dangerous building.

　　Residents of this building told reporters,Now the streets can live in resettlement houses according to their wishes, or enjoy the monthly subsidy from 1000 yuan to rent their own houses.

　　Household:They said that you should put your mind at ease. Now this house must not be demolished, and it will be done after it is handled. Move out first. The government gives a family 1000 yuan a month, and we rent a house outside.

　　Zhong Hongxia, member of the Standing Committee of Haikou qiongshan district District Committee and Minister of Propaganda Department, told the reporter that the first priority at present is to let residents move out of dangerous buildings and stay away from danger.Those who are willing to live in resettlement houses can move in immediately, and those who want to rent outside are also subsidized. The investigation of relevant responsible units such as the Housing and Construction Bureau has begun.But it takes time.

　　Zhong Hongxia:We have all found housing outside for free for these original tenants, and we have provided some funds, but it is only a transitional period. We want to demolish and rebuild the house as soon as possible, because it takes time to involve some details.

△ Building 27, Qingzhu Street, on the left, can be seen to be obviously inclined.

Government of qiongshan district: WillConduct a thorough investigation

Seriously investigate the responsibility according to the law and regulations

　　The government of qiongshan district said in a circular, "The responsible person of Fengxiang Street, which has poor control over dangerous buildings, will be held accountable.And instructed the relevant departments to thoroughly investigate the suspected violations of the dangerous building reflected by the masses in the process of approval, construction and sales.Seriously investigate the responsibility according to the law and regulations."

　　Zhong Hongxia told reporters that who should pay for the demolition and reconstruction costs that residents are concerned about,If it is the responsibility of the construction applicant or the housing construction department in that year, then the relevant expenses should also be borne by the responsible person.

　　Zhong Hongxia:Which department is this illegal approval and sales? Which link is it? Who has a problem? We will arrange for further accountability, for example, the contractor at the beginning. After investigation, if he violates the rules, he will bear the main responsibility. According to the law, he should pay the expenses.

　　Voice of China will continue to pay attention to the progress of the incident.

Wen | Zero One

As the most popular drama in the summer, the bleak opening of "Feng Shen: Chao Ge Fengyun" (hereinafter referred to as "Feng Shen 1") is beyond expectations. The box office on the first day and the next day were 49 million and 58 million respectively, which were far lower than expected, which directly led to the stock price of Beijing Culture falling.

Fortunately, the film market is booming, and the score of Douban of Fengshen 1 is about 7.8 points and the favorable effect of social platforms have also begun to exert their strength. Fengshen 1 has reached more than 100 million box office in the first weekend, and has accumulated nearly 700 million yuan in the past week, which finally makes the filmmakers and the audience who love this film breathe a sigh of relief.

If the first film can finally reach the box office score of 2 billion+,the pressure on investors will not be too great, at least the second and third films will be "worth seeing"; But on the other hand, it can’t reach the long-awaited goal of domestic masterpieces, and the impact on box office records is expected to be placed in the second and third films with more magical scenes.

Feng Shen 1 is a film that is difficult to evaluate. Reading Entertainment tried to interpret the impression of this film from different angles: as a reinterpretation of traditional mythological images and a story conception, as the opening of a trilogy epic, and as the first truly industrialized commercial film of China’s traditional mythological story, it deserves different evaluations from different angles.

Because of the household name of the story, the thin limitation of the original novel in plot and characterization, and the failure of previous big-screen adaptations, public opinion was extremely harsh on "Feng Shen", and it suffered a large-scale "magnifying glass" stab before its release.

The original work of "Romance of the Gods" almost only emphasized fate, but now it seems that there are quite a few parts of "three incorrect views". And the characters in the original story are mostly storytelling and relatively paper-based. The primary problem to be solved in the trilogy of "Feng Shen" is the script, from which angle to cut into the world of Feng Shen Romance, and how to shape those well-known characters.

As a result, director Wu Ershan and the creative team chose a bold and prudent direction.

The story of "Fengshen 1" can be said to revolve around Yin Shou, the Shang king. Around the shaping of Yin Shou, the core figure, other core figures have the conflict point of the progressive story:

Yin Shou, the Shang King played by ChristianRandPhillips, has become a new interpretation of the character "Zhou Wang". His early heroic temperament, demagogic speeches, the release of ambition after receiving the help of the fox demon, his great desire for power and extreme selfishness finally broke out, and the characters have a credible and strong sense of flesh and blood and emotional rendering.

Yin Shou is the source of disaster behind da ji, the "demon queen". Da ji’s appearance was portrayed as a natural and animalistic monster image. She didn’t help or confuse Yin Shou out of any human social interests, but simply thanked Yin Shou for helping him achieve any goal. Her ability has become the external cause of exposing Yin Shou’s wild heart to the world, but in essence Yin Shou only went from hiding to not hiding, and its inner nature has never changed.

Yin Shou was Yin Jiao’s father and Ji Fa’s "spiritual father" in the proton period. Ji Fa’s growth path is to break the "absolute correctness" behind Yin Shou’s image as an idol of life and a spiritual father. Since then, Ji Fa has been able to make decisions with truly independent self-thinking and moral ideas. Ji Chang’s sentence "It doesn’t matter whose son you are, but who you are" is exactly the case.

Yin Shouben should have been recognized by Bigan, Ji Chang, other Shang courtiers, vassals and even overseas immortals as "the common master of the world". With all kinds of evil deeds of his ambitious expansion exposed, natural disasters and visions appeared, and the Shang King also lost the people’s hearts and the protection of heaven and earth. Four Bo Hou were killed, and Jiang Ziya fled with the list of deities, and the tone of the whole story of deities was basically stable in epic temperament.

"Zhou Wang" is often regarded as a somewhat stupid, brainless and fatuous dissolute emperor in the original works and past film and television works. If we don’t break away from the traditional narrative mode of obsessing the Lord after the demon, then the whole temperament concept of the new deity will be extremely old and boring. There are two advantages in the way the film "Feng Shen" is handled:

First, it is in line with modern values and historical truth. The fallacy of the narrative logic of "femme fatale" lies in the fact that "power is never in the hands of femme fatale", and whoever is the inflated ambition and evil deeds should be counted on; The second is to create fuller and more hierarchical characters. Zhou Wang and da ji are both more tenable and in line with narrative logic.

Therefore, from the perspective of reinterpretation of traditional mythological images and story conception, Reading Entertainment believes that "Feng Shen" has been done quite well, and it is not an exaggeration to score 85 points.

As early as the establishment of the trilogy, Wu Ershan’s shooting idea of "Three continuous shooting" was very similar to that of Peter Jackson’s filming of the The Lord of the Rings trilogy.

From the perspective of film shooting, the benefits of "Three continuous shooting" are that the total cost is easier to control and the total efficiency is higher. For example, from the perspective of actor’s pay, "Three continuous shooting" has no risks brought by the change of casting schedule and coffee spot, and continuous shooting’s pay is easier to depress, without considering the rising cost or the risk of changing roles brought by the sudden popularity of new actors in a few years. The same is true in terms of film preparation and team understanding.

Middle-aged and elderly actors like ChristianRandPhillips and Li Xuejian, and newcomers like Na Ran, if they are filmed separately in the long period of trilogy release, it is difficult to ensure the consistency of the lineup. However, under the model of "Three continuous shooting", middle-aged and old-aged actors can complete their own scenes in a coherent way, and new actors can also dig from sea selection to comprehensive customized training for their roles. The amazing performance of Na Ran as da ji is also largely related to this way of actor selection and training.

From the narrative point of view, Feng Shen 1 also plays the same "opening" role as The Ring Messenger. In The Lord of the Rings’s trilogy, most of the big scenes also come from the second and third films, and there is almost no big war drama in the first film. If only from the perspective of establishing the foundation of the world outlook and stimulating the audience’s interest, the story of "Feng Shen 1" is quite well laid out, and the audience will be highly interested with the eggs that Ji Fa came home at the end of the film and heard that Master Tai was still in court.

Therefore, as the grand opening of the trilogy epic, "Fengshen 1" is definitely above the pass.

However, there is an obvious misjudgment between Feng Shen 1 and the expectations of the general audience. The vast majority of the audience think that "Feng Shen 1" is a masterpiece of China’s magical mythology, but in fact, as the opening of the trilogy epic film, there are few magical and magical scenes in the feature film of Feng Shen 1, focusing on the short appearances of, Lei Zhenzi and others. The overall tone is a relatively heavy costume style, and the audience will feel that kind when Master Wen appears with the eggs that will be returned to the DPRK by the four devils.

Therefore, when everyone said "one person, one vote for Master Wen’s travelling expenses", it reflected the audience’s high expectations for the follow-up story of fighting. After all, that is the mythical story of deity in everyone’s impression. It is most important for director Wu Ershan to raise the visual wonders of domestic films in the mythical field to a higher level, as The Wandering Earth did in the field of science fiction.

But from this point of view, Reading Entertainment Jun thinks that "Feng Shen 1" is not successful. The film’s service aesthetic level is online, and the lens language texture is also in place, but the CG special effects level is not outstanding. The opening performance of Jizhou World War I is comparable to Canon’s international first-class blockbuster, while other special effects highlights have some make a fool of oneself:

One is that Jiang Ziya and his party were arrested, and elephants came in the background. The CG matting of the whole picture was very rough, which was almost or even slightly less than that of Hollywood’s clash of the titans ten years ago. The second is that in all scenes of Lei Zhenzi, the details such as skin and wings are also rough; The third is that some scenes are rough, and the scenes of Kunlun Mountain and Shen Gongbao in the sea have no features and memory points, while the cliffs and floods that Ji Fa fled also smell like domestic 3D animation.

As for the scenes in Yang Jian and Nezha films, they are basically when couriers are forced to go offline. Basically, what you can see in the trailer is the essence of them in the feature film. Therefore, when it comes to domestic visual effect blockbusters, Fengshen 1 can only be said to have achieved part of it, and it is difficult for the public to have an intuitive upgrade feeling like that in Wandering Earth 2. The audience can only look forward to Fengshen 2 and 3.

If it hadn’t been for July 2023, the strongest summer file in history, and the unparalleled trend of domestic films since 2023, the box office trend of "Fengshen 1", which was only 100 million in the first two days, would probably slide into the abyss and eventually be less than 1 billion, and the cost pressure of the second and third films would increase sharply, and the release progress and quality would probably be greatly affected.

Word-of-mouth proves that the quality of Fengshen 1 is not bad, and the main reason why it falls into such a dangerous situation is the complete failure of the previous publicity: First, almost none of the lightning spots to be avoided and the negative impressions to be reversed have been achieved; Second, there is no stalk.

On July 21st, the day after its release, Fengshen 1 ranked as high as 28.2%, and the attendance rate was only 8.9%, while the attendance rate of Chang ‘an Three Wan Li was 23.2%, and that of Octagonal Cage was 19%. Even the Super Family with a score of 4 was 10%. The extremely low attendance rate can be seen in the early announcement of Fengshen 1.

Because of the "3 billion cost" stunt thrown in the early days and the mythological theme, the project "Feng Shen" reminds people of a large number of domestic bad films instantly, while "Feng Shen" invited foreign special effects experts from The Lord of the Rings, which is inconsistent with the emphasis on promoting domestic blockbusters in the past two years, making people afraid that this is another monster of "combining Chinese and Western". The pre-publicity of "Feng Shen" should avoid and reverse these impressions.

As a result, until the film was released, most viewers’ impression of the film was still "a domestic blockbuster with a cost of 3 billion and I don’t know where the flowers went." There is no public reaction to the complexity and heavy publicity costumes and exquisite makeup. The released trailers will only make the audience feel bad one after another. The released stills posters are 108,000 miles better than the effect of the positive film, and Lei Zhenzi’s picture with poor effect is circled.

As for "no stalk", the early stage is normal, because all the young actors are newcomers, and they don’t have a familiar face. Naturally, they can’t bring their own controversy as YiBo and Jackson Yee did when they participated in movies. However, this topic has great potential and publicity has not been made good use of.

Da ji, played by Na Ran, was controversial, so it was difficult to explain it without spoilers. The film originally chose to hide, but when it came to the end, it didn’t hide the footage and the interview of imitating the fox. This way of "I spent a lot of time" didn’t work well, because the audience didn’t quite understand the animal shape of the fox side in the film, and as a result, one of the most amazing characters in this feature film had a counterproductive effect before the screening. It was better to hide it all the time.

Almost all the "stalks" in "Feng Shen 1" are ignited in the running water logic of "I make suggestions for Feng Shen", but the propaganda materials in the early stage have hardly played any positive role.

Therefore, "Feng Shen" is "a thrilling pass with a grand opening" because as the first part of a trilogy, "Feng Shen 1" has become its own task from the film content itself, which not only has the story tension of an independent chapter, but also shapes a complex villain and a growing decent figure, and also successfully stimulates the audience’s interest in the sequel. However, from the market point of view, "Fengshen 1" can only be said to have passed the risk and just passed the line of life and death.

* Original article, please indicate the source when reprinting.

In the Mid-Levels Valley Garden in Yantian District, resident Zhang Shuying showed reporters how to drink direct drinking water.

　　Turning on the tap and filling the glass with tap water, Zhang Shuying, who lives in Building 2 of Banshan Valley Garden in Yantian District, drank it without hesitation. "This water is delicious, and I feel better than foreign direct drinking water."

　　In April 2019, Yantian District realized direct drinking of tap water in the whole district, which is also the first administrative district in the city to realize direct drinking of tap water. It is estimated that by 2023, Shenzhen will achieve full coverage of direct drinking water in all central cities, and in 2025, it will achieve direct drinking water in the whole city.

　　The day when you turn on the tap and drink is getting closer and closer to all Shenzhen people.

　　Yantian district is the first in the city to realize direct drinking of tap water.

　　Yantian District, where Mid-Levels Valley Garden is located, is the first administrative district in Shenzhen to realize direct drinking of tap water.

　　Yantian District has a small area, only 74.99 square kilometers, and the municipal water supply network is 220 kilometers long. Hu Ping, an engineer of Yantian District Water Affairs Bureau, said that although the ontology conditions are good, some municipal pipe networks in the whole region use rustable pipes such as welded steel pipes and gray cast iron; In some residential areas, due to the different quality standards of development and construction units, yellow water, rusty water and high leakage rate of pipe network are common; In other communities, there is no distinction between the production and consumption of the second supply pump room (domestic water and fire water), the level of property management is low, and the irregular cleaning of the pool water tank causes secondary pollution.

　　In 2012, in order to improve the quality of life of residents, Yantian District Committee and Government took the initiative to start the renovation project of high-quality drinking water pipe network in the city. This also provided experience for the later implementation of the high-quality drinking water household project in the whole city. Subsequently, Yantian District successively carried out various work of drinking tap water directly, and solved all kinds of historical problems in a package. City Water Group actively cooperated in the construction process to provide supporting water meters, valves and other equipment.

　　Since 2012, the municipal, district government and water group have invested a total of 947 million yuan, and successively completed the upgrading and renovation of the double-source Yantian branch line, two main water plants, 13.09 km old municipal water supply pipe network, water supply pipe network of about 40,000 residential quarters in 222 communities, 4 municipal pressurized pump houses and secondary water supply facilities in 131 communities. At the beginning of 2019, the work of drinking tap water directly in Yantian District passed the evaluation of an expert team headed by Academician Qu Jiuhui, and the first demonstration zone of drinking tap water directly in Shenzhen was officially built. By the end of 2021, Yantian District will also achieve full coverage of meter reading in residential quarters, and the whole chain of water plants, municipal pipe networks, residential pipe networks and secondary water supply facilities in the whole district will be professionally managed, so that residents’ water safety will be more guaranteed.

　　Five water plants in our city have built advanced treatment processes.

　　The quality of tap water is directly related to the health and quality of life of the citizens. However, when water enters thousands of households from nature, it mainly goes through three stages: water source project, waterworks and water supply pipe network. After flowing into high-rise residential areas, it needs secondary pressurization, so the problem of secondary water supply facilities arises. For Shenzhen, except for a small amount of local self-produced water, the water source mainly comes from Dongjiang outside the city, and the water quality is excellent and stable. Therefore, whether tap water can meet the standard of direct drinking depends on the water plant, the pipe network and the facilities for supply.

　　Less than 1 km away from the northwest of Shenzhen North Railway Station, which is densely populated, is the location of Shenzhen Longhua Redwood Landscape Factory. In December, 2020, the second phase project of Redwood Shanshui Factory was completed and put into water, with a new conventional treatment capacity of 150,000 cubic meters/day and an advanced treatment capacity of 300,000 cubic meters/day, making it the first modern water plant with advanced treatment technology outside the original special zone.

　　Sun Jun, chairman of Deepwater Longhua Water Company, said: "The successful completion of the Redwood Landscape Factory has laid a solid foundation for Longhua District to realize direct drinking of tap water, created a replicable and scalable experience for the new renovation and expansion of the city’s water plants, and also made up a key link for the balanced and full coverage of water supply services in all districts inside and outside the original special zone."

　　Yang Qun, director of the Water Resources and Water Supply Security Department of Shenzhen Water Affairs Bureau, said that in recent years, the city has continuously increased the new renovation and expansion of waterworks and the upgrading of standards. At present, five waterworks, including Bijiashan, Meilin and Hongmushan, have built advanced treatment processes with a total capacity of 1.27 million cubic meters per day. At the same time, Miaokeng, Baguang and Jiazitang waterworks are under new (expanded) construction, the second phase expansion project of waterworks in large industrial zone is about to enter the site, and more than 10 waterworks such as Nanshan and Donghu are under preliminary work; In the future, our city will also shut down a number of small water plants with low early construction standards.

　　"It is estimated that by 2025, through the integration of waterworks, the total number of waterworks in the city will be about 30, with a total water supply capacity of 8.44 million cubic meters per day, all of which are equipped with advanced treatment processes, which means that the basic conditions for producing direct drinking water are available." Yang Qun said.

　　The city will complete the renovation and upgrading of pipe network and secondary supply facilities next year.

　　Compared with the bidding of waterworks, the transformation and upgrading of pipe network and secondary supply facilities are more complicated because of their many points and wide areas.

　　Yujing Huacheng, located in Futian Street, is a large community in Futian District, consisting of 7 high-rise buildings for commercial and residential use, with a total of 3,580 households and more than 10,000 people. In the pump room on the second floor of the basement, six temporary water supply pumps are roaring, and the workers are preparing to dismantle the old pumps, which will be completed in a few days.

　　"The old pump is big and heavy, and the temporary pump and the new pump are only half the size of the old pump, which is more stable and energy-saving." Long Ling Feng, the site manager of the second water supply project of Liyuan Water Design Consulting Company, told the reporter that the renovation of Yujing Huacheng will implement the high-quality drinking water project and the second water supply facility upgrading project simultaneously, which will save time and coordination cost compared with separate construction.

　　Among them, the high-quality drinking water project will transform the old buried water supply pipeline into ductile iron pipe and the exposed pipeline into 316L thin-walled stainless steel pipe; The upgrading of secondary water supply facilities will separate the existing pool for domestic fire fighting, thus reducing the residence time of water flow. The original concrete pool wall of the pool is covered with food-grade ceramic tiles, and the water pump, pipes and fittings in the pump room are made of 316L stainless steel, which will significantly improve the water supply quality of the community.

　　The reporter learned from Shenzhen Water Affairs Bureau that in terms of pipe network, since 2013, our city has successively carried out two high-quality drinking water household projects. The renovation funds are borne by the city and district according to the ratio of 1:1, and the water supply enterprises bear the cost of user water meters and supporting valve groups. The scope of renovation mainly includes the total water meter in the community, user sub-meters, municipal pipe network and the water supply pipes between each user’s household location. After the renovation, it will be handed over to the water supply enterprises for maintenance and management, and the water supply enterprises will realize meter reading to households. In the first phase of the city, the renovation project of the old water supply pipe network in about 1050 residential quarters was completed, and the project effect was good; At present, the renovation of 1000 residential areas has been completed in the second phase, and it is estimated that by June 2022, the renovation of the old water supply pipe network in the remaining residential areas will be completed.

　　In terms of secondary water supply facilities, at the end of 2018, the city started the upgrading project of secondary water supply facilities in residential areas of the city. The renovation funds were borne by the city and district according to the ratio of 1:1, and the water supply facilities such as pump houses, pools (boxes), pumps and monitoring equipment in about 2,900 residential areas in the city were upgraded. At present, all districts have fully entered the construction site, and more than 300 residential renovation projects have been completed. It is expected that all renovation tasks will be completed by the end of 2022. After the renovation, the water supply facilities in the community will be handed over to the water supply enterprises for maintenance and management, and the water quality and water pressure will be effectively improved, further improving the water supply service level of the whole city.

　　After the completion of these two projects, and the implementation of the upgrading of water plants, direct drinking of tap water will be realized in various districts of Shenzhen.

CCTV News:"Winning the bid" is the "first step" of the project. As a leading indicator reflecting the investment enthusiasm, "winning the bid in the project" has the meaning of "wind vane". Next, we will feel the fiery investment through the winning bid data.

According to the data of the National Information Center, in the first two months of 2023, the number of winning projects increased by 45.5% compared with the same period of last year, among which the number of winning bids and the year-on-year growth rate in the eastern region both led the way; Construction projects are "ballast stones" for stable investment, and the number of winning projects far exceeds other fields.

At the same time, the sales volume of construction machinery and equipment is also strong this year. According to the data of China Construction Machinery Industry Association, in February, the sales volume of various crawler cranes increased by 60.5% year-on-year, the sales volume of road rollers increased by 16.1%, and the sales volume of various pavers increased by 28.4% year-on-year.

Yang Daoling, Director of Big Data Analysis Division of Big Data Development Department of National Information Center:On the whole, a number of high-frequency data show that since the beginning of this year, all localities have made every effort to expand effective investment and promote the "acceleration" of project construction, and the signs of rapid recovery of project construction heat are obvious.

From another leading indicator of infrastructure investment, 1-mdash; In February, the planned total investment of newly started projects increased by 11.8% year-on-year, and the invested funds increased by 12.5%, which provided a strong guarantee for the sustained and steady growth of investment.

Zhang Liqun, Researcher, Macroeconomic Research Department, the State Council Development Research Center:The driving role of infrastructure investment has been further strengthened, the trend of stabilizing real estate investment has gradually become obvious, and the enthusiasm of enterprises to invest has gradually increased. Therefore, the whole investment is the basic trend of overall recovery this year, and the key role of investment in expanding domestic demand will be significantly enhanced in improving the quality of supply and improving people’s livelihood.

CCTV News:Dragon boat race, chopping waves, making zongzi, hanging wormwood and making sachets, during the Dragon Boat Festival, various places carry out colorful folk activities, which are full of strong Dragon Boat Festival culture everywhere.

Jingxian County, Anhui Province: Taohuatan Water Dragon Boat Race attracts tens of thousands of people.

On the morning of June 21st, in Taohuatan, Jingxian County, Xuancheng County, Anhui Province, a lively Dragon Boat Festival started with drum beating. The contestants are all local villagers. A total of 31 teams participated in the Taohuatan Dragon Boat Race this year, with about 1,200 participants. Among them, more than half of them are working in other places and specially rushed back to their hometown to participate in the competition. In recent years, the "Dragon Boat Village Race" in Taohuatan has become more and more famous and attracted more and more tourists. This year, the total number of people watching the dragon boat race is expected to exceed 10,000.

Wuhan, Hubei Province: Dragon Boat Race for the Best.

In Dongxihu District, Wuhan, Hubei Province, a dragon boat race with the participation of the whole people began with great excitement. In the tight drums, the players shouted neat songs and made uniform movements. Qi Xin joined forces to sprint to the finish line. The dragon boat race is a 500-meter straight race, which is divided into two days. A total of 31 teams participated in the race, the oldest being 52 years old and the youngest being 9 years old.

Dong Binbin, a dragon boat player:Everyone is United as one, and we are twisted into a rope on the boat. We have an indomitable spirit and a champion’s heart.

Pingtang, Guizhou: Inheriting Folk Custom and Making Glutinous Dumplings for the Dragon Boat Festival

Near the Dragon Boat Festival, in Datang Town, Pingtang County, Qiannan Prefecture, Guizhou Province, the local Miao people have been busy making dumplings early. People washed and dried the fresh leaves of zongzi, fried glutinous rice, and added plant ash made of glutinous rice straw for seasoning. After the materials were prepared, the elders and young people in the village wrapped zongzi together.

Sichuan Linshui: Dumplings in ancient courtyards are fragrant, and thousands of people compete to make dumplings.

In Tanjia Courtyard, Yuanshi Town, Linshui County, Sichuan Province, local villagers and agricultural technicians gathered together to hold a contest of making dumplings for thousands of people. On the courtyard dam, the contestants skillfully made zongzi, and soon, beautiful and strong pointed zongzi were wrapped, and laughter filled the century-old courtyard, showing a strong festive atmosphere.

Ji ‘an, Jiangxi: Weaving eggs and hanging wormwood in the Dragon Boat Festival is traditional and fashionable.

In Aicaotang, Chenkeng Village, Meitang Town, Ji ‘an County, Jiangxi Province, villagers, volunteers and school teachers and students weave an egg pocket with colorful ropes. After weaving, they put the boiled eggs in the bag and hang them around the children’s necks.

Dai Fengying, teacher of Meitang Primary School in Ji ‘an County, Jiangxi Province:Weaving an egg pocket with colorful ropes is first of all a moral that adults place on children, that is, they hope that they can be safe after hanging up the egg pocket.

Teachers and students also use fresh wormwood and calamus with beautiful summer flowers to make traditional and fashionable wormwood bouquets.

Tongwei, Gansu: Mulan soup with cinnabar traditional folk custom welcomes Dragon Boat Festival.

In the Tongwei County Museum in Dingxi City, Gansu Province, children dressed in Hanfu lined up and washed their hands with herbal medicine in turn. The museum staff lit cinnabar on their foreheads to wish them good health and peace.

Recently, we learned from foreign media that a new generation of BMW 5 Series and i5 will be launched on May 24th. It is understood that the new car will launch a fuel version and a plug-in version, and will also launch an i5 pure electric version.

In terms of appearance, the new car adopts the family’s iconic kidney front grille with sharper headlights, matching the design of the through front enclosure, and the whole front looks very slender and exquisite.

On the side of the car body, the side lines of the new car run straight through, with the slightly slip-back shape and the design of the hidden door handle, the whole car body looks slender and atmospheric.

In the rear part, the rear design of the new car is relatively regular, and the slightly upturned "little ass" is matched with the newly designed taillight group, which looks fashionable and dynamic as a whole. In terms of power, the long-wheelbase version will use two kinds of gasoline engines, and the new car will continue to use the 2.0T engine and join the 48V light mixing system, and it is expected to follow the naming of 525Li and 530Li. We will continue to pay attention to more news about the new car.

　　() F10 data shows that on March 3, 2024, the theme points of () were updated and adjusted:

　　Have their own AIGC technical route.

　　On February 10, 2023, the company disclosed on the interactive platform: At present, the company has its own AIGC technical route, which is mainly divided into two categories: the first category is mainly based on small visual samples, which realizes image generation in various scenes, lighting, angles, etc. Compared with public or other company technologies, it has the advantages of only requiring a small number of training samples, scene mobility and strong generalization ability. The second is based on language generation model, which is applied in robot dialogue.

　　Huawei Shengsi

　　V1.0, the joint solution for smart worksite of Shengshi Technology Co., Ltd., and Shengsi MindSpore, the AI framework of Huawei Technology Co., Ltd., have completed the compatibility test, and are hereby granted the right to use HUAWEI COMPATIBLE certificate and certification logo, valid for October 2022.

-October 2025.

　　Hainan Free Trade Port Closed for Operation

　　As an extension of the port, the special customs supervision area is the key market of the company in recent years. The company set up the Smart Customs Division, focusing on following up the relevant market demand. In 2022, the company successfully won the bid for Xiong ‘an Free Trade Zone (Comprehensive Bonded Zone) and other projects, and closely followed the market demand of Hainan Free Trade Port, and achieved fruitful results. In 2021, the company invested and set up a wholly-owned subsidiary in Hainan, and equipped with a special team to closely track the market demand of Hainan Free Trade Port. During the reporting period, the consortium led by the company successfully won the bid for Haikou xiuying port Project, Haikou Xinhai Port and Nangang Project, and the company independently won the bid for Sanya Port Nanshan Port Project, haikou meilan international airport Port Inspection Infrastructure Upgrading and "Second-line Port" Function Construction Project, Sanya Phoenix Cruise Port Project and Sanya International Yacht Center Port Construction Project, which won the first battle and laid a solid foundation for the company to further tap the follow-up market demand of Hainan Free Trade Port and seize market opportunities. 2023, as a "key year to promote the customs clearance operation of the free trade port", will speed up the construction of software and hardware for customs clearance operation, and the company will also closely follow the relevant demand, so as to build a benchmark project, accelerate the promotion of the market of special customs supervision zones in other regions, open up a new business situation, and promote the business of special customs supervision zones to become a new business growth point of the company.

　　Accelerated replacement of domestic platforms

　　The company continued to increase investment in R&D, continued to promote the localization process, fully implemented the localization strategy in embedded software and hardware, intelligent terminal products, operating systems, databases and other aspects, and continuously improved the safety of products. In 2022, many products of the company have been adapted to the HarmonyOS operating system, and some products have obtained the compatibility certificate of the National Open Atomic Open Source Foundation. The MVNTR team’s "Smart Coal Mine Solution Based on AI Video Perception" project participated in Shengteng AI Innovation Competition 2022, a top competition for AI developers, and won the gold medal in Shenzhen Division, demonstrating the company’s innovative research and development strength in the AI industry. Based on the AIoT platform, the company accessed niche products and extended them to core products, including AI smart cameras, AI intelligent terminals, AI servers, etc., constantly enriching product lines, and making technological innovations in products and technologies to enhance competitiveness to meet market demand.

　　Multi-modal large model technology

　　ChatGPT-like applications hatched by the company based on multi-modal large model technology have been verified in domestic border inspection and customs. In addition, based on intelligent sensing terminal, intelligent inspection robot and application of AI algorithm, integrating multi-level command and dispatch technology and AR visualization technology, the company has newly created and promoted a variety of AI-integrated smart port 2.0 innovation modes, helping global customers to create a port economy with regional characteristics, promoting port informationization and intelligent upgrading, and continuing to consolidate the company’s leading position in the field of smart ports. In terms of identity authentication products, the company aims at non-contact identity authentication, and has developed a series of products such as face recognition, iris recognition, palm vein recognition and multimodal biometric terminal. Combined with years of industry experience, the algorithm model has been continuously optimized, which has overcome many difficult problems in special environments and achieved good results.

　　The ecosystem continues to expand, and AIoT welcomes new product lines

　　The company steadily promotes the diversification strategy, gives full play to the company’s technical and ability advantages, and expands its product line with one heart. Following the series products of port industry, various intelligent terminal products such as video surveillance, robot, car networking and identity authentication have also joined the company’s AIoT ecosystem, laying a solid foundation for continuous improvement of business layout. In addition, in order to build a product ecology, the company integrated R&D resources, and based on the trend of the times, built an infrastructure platform-the intelligent IOT platform. The platform takes the flexibility and controllability of edge computing as the core, improves the terminal’s perception and execution ability, enhances the effectiveness of data gathered by devices on the platform, gradually expands the platform’s business ability and command and dispatch ability, builds a business middle platform with the middle platform of AIoT technology as the core, realizes the interconnection of information equipment, unifies the equipment access standards and data convergence, provides the industry users with central AI ability, and finally forms an all-things-connected ecosystem built by many business systems.

　　Complete a number of extension investment M&A projects.

　　Through capital increase, newly-established equity participation or wholly-owned acquisition, the company completed a number of overseas investment M&A projects, broadened business development channels, further improved the company’s business map, and used its own funds of 24 million yuan to invest (transfer equity to increase capital) in Beijing Nano Metropark Technology Co., Ltd., holding a total equity of 0.9554% in Nano Metropark. Through the cooperation with Nano Metropark, we actively deployed the medical field, and subscribed for 35% of Guangdong Hengyuan Chuangzhizao Industrial Investment Partnership (Limited Partnership) with our own funds of 52.5 million yuan. The industrial fund focuses on intelligent manufacturing, intelligent application-related advanced technologies such as artificial intelligence, big data, Internet of Things, optoelectronics, integrated circuits, cutting-edge applications and investment opportunities in the upstream and downstream of the industrial chain. Participating in the establishment of the industrial fund this time will help the company to better grasp the investment opportunities with the help of professional investment institutions, rich project reserve resources and perfect risk control system, and use its own funds of 48 million yuan to subscribe for Hainan Shengxingtong Enterprise Management Partnership (Limited Partnership) The partnership invested in Asia-Pacific Satellite Broadband Communication (Shenzhen) Co., Ltd., and by subscribing for the share of the partnership, the company can quickly cut into the field of satellite communication and expand the opportunities for asset appreciation. As of the disclosure date of this report, the partnership has completed the transfer of 3.1071% equity of Asia-Pacific Satellite Broadband Communication (Shenzhen) Co., Ltd., with a total of 21% of its own funds raised.The acquisition of 100% equity of Shenzhen Baertl Robot Co., Ltd. for 8,030,100 yuan, on the one hand, solved the site problem of some fundraising projects in Shenzhen, on the other hand, brought fire fighting robots into the company’s product system, improved the company’s robot product line and enhanced the comprehensive strength of the company’s robot business. As of the disclosure date of this report, the industrial and commercial changes and handover of this acquisition have been completed. With its own capital of 20 million yuan, Nanjing Shishi Technology Co., Ltd. holds 1.60% equity of Shishi Technology after the capital increase. By combining the advanced technology of Shishi Technology in the field of brain-like intelligence and the company’s overall solution design and implementation ability, we hope to provide some original and differentiated industry solutions in various intelligent scenarios and improve our company’s artificial intelligence industry. As of the disclosure date of this report, the project investment contract has been signed, industrial and commercial changes and other work are being promoted, and the cooperation of related projects is also being promoted.